Quantitative read-across structure-property relationship (q-RASPR): a novel approach to estimate the bioaccumulative potential for diverse classes of industrial chemicals in aquatic organisms.

The Bioconcentration Factor (BCF) is used to evaluate the bioaccumulation potential of chemical substances in reference organisms, and it directly correlates with ecotoxicity. Traditional BCF estimation methods are costly, time-consuming, and involve animal sacrifice. Many technologies are used to avoid the problems associated with testing.

Chemometrics-driven prediction and prioritization of diverse pesticides on chickens for addressing hazardous effects on public health.

The extensive use of various pesticides in the agriculture field badly affects both chickens and humans, primarily through residues in food products and environmental exposure. This study offers the first quantitative structure-toxicity relationship (QSTR) and quantitative read-across-structure toxicity relationship (q-RASTR) models encompassing the LOEL and NOEL endpoints for acute toxicity in chicken, a widely consumed protein. The study's significance lies in the direct link between chemical toxicity in chicken, human intake, and environmental damage.