Water pollution is nowadays a global problem and the effective detection of pollutants is of fundamental importance. Herein, a facile, efficient, robust, and rapid (response time < 2 min) method for the determination of important quinone-based industrial pollutants such as hydroquinone and benzoquinone is reported. The recognition method is based on the use of screen-printed electrodes as sensing platforms, enhanced with carbon-based nanomaterials.
View Article and Find Full Text PDFSingle-walled carbon nanotubes (SWCNTs) demonstrate a strong potential as an optically activated theranostic nano-agent. However, using SWCNTs in theranostics still requires revealing mechanisms of the SWCNT-mediated effects on cellular functions. Even though rapid and delayed cellular responses can differ significantly and may lead to undesirable consequences, understanding of these mechanisms is still incomplete.
View Article and Find Full Text PDFTheranostics is the emerging field of medicine that uniquely combines diagnostic techniques and active agents to diagnose and treat medical conditions simultaneously or sequentially. Finding a theranostic agent capable to cure the affected cells and being safe for the healthy ones is the key for successful treatment. Here, we demonstrate that agglomerated single-walled carbon nanotubes (SWCNTs) are promising theranostic agent that enables photo-activated 'cold' destruction of the cancer cells keeping their environment alive.
View Article and Find Full Text PDFThe composites and thin films comprising individual single-walled carbon nanotubes with a polymer coating (p-CNTs) have been prepared and their electromagnetic responses have been studied in a wide range from low-frequency (25-10 Hz) up to the infrared region. In spite of the high volume fraction of the nanotubes (up to 3.3%), the polymer coating prevents direct p-CNT contacts and the formation of the percolation network in those composites, so that p-CNTs interact only via the electromagnetic coupling.
View Article and Find Full Text PDFBack Ground: Maternal nutritional status influences the developmental environment of the fetus which consequently affects the birth weight of the newborn. However, the association between maternal nutritional factors and birth weight is complex and is not well characterized in Ethiopia.
Objective: To assess the effect of maternal anthropometry and biochemical profile on birth weight of babies at Butajira Referral Hospital, Butajira, Ethiopia.
Nanotechnology
September 2018
The microwave conductivity and permittivity of both single-walled and multi-walled carbon nanotube (SWCNT and MWCNT) sponges were measured while compressing the samples. Compression leads to a huge variation of the absorptance, reflectance, and transmittance of the samples. The dependence of the microwave conductivity on the sponge density follows a power-law relation with exponents 1.
View Article and Find Full Text PDFThe electrical properties of conducting meshes are investigated numerically by solving the related Kirchhoff equations with the Lanczos algorithm. The method is directly inspired by the recursion technique widely used to study the electronic and vibrational spectra of solids. The method is demonstrated to be very efficient and fast when applied to resistor networks.
View Article and Find Full Text PDFJ Opt Soc Am A Opt Image Sci Vis
April 2016
The excitation of modes of an open-face slab waveguide by light incident on a thin-film photovoltaic solar cell with a periodically corrugated metal backreflector is indicated by peaks in the absorptance spectrum. An absorptance peak due to the excitation of a waveguide mode (WGM) can split as the corrugation depth increases. The splitting can be explained in terms of the wavenumbers of the WGMs of two open-face slab waveguides with different thicknesses of the semiconductor layer.
View Article and Find Full Text PDFThe rigorous coupled-wave approach (RCWA) is extensively used to compute optical absorption and photon absorption in thin-film photovoltaic solar cells backed by 1D metallic gratings when the wave vector of the incident light lies wholly in the grating plane. The RCWA algorithm converges rapidly for incident s-polarized light over the entire 400-1100 nm solar spectrum. It also performs well for incident p-polarized light in the 400-650 nm spectral regime, but even with a large number of Floquet harmonics in the solution, the total reflectance is underestimated in the 650-1100 nm spectral regime.
View Article and Find Full Text PDFTo decrease single-wall carbon nanotube (SWCNT) lengths to a value of 100-200 nm, aggressive cutting methods, accompanied by a high loss of starting material, are frequently used. We propose a cutting approach based on low temperature intensive ultrasonication in a mixture of sulfuric and nitric acids. The method is nondestructive with a yield close to 100%.
View Article and Find Full Text PDFElectromagnetic absorption and subsequent heating of nanoparticle solutions and simple NaCl ionic solutions is examined for biomedical applications in the radiofrequency range at 13.56 MHz. It is shown via both theory and experiment that for in vitro measurements the shape of the solution container plays a major role in absorption and heating.
View Article and Find Full Text PDFUnlabelled: It is proposed to use the novel paradigm of treating cancer with hyperthermic therapy using multi-walled carbon nanotubes (MWCNT) stimulated with near infrared (NIR) irradiation.
Aim: To establish the capacity of MWCNT stimulated with NIR irradiation to destroy Erlich ascitic carcinoma (EAC) cells.
Materials And Methods: EAC cells suspension was irradiated with NIR heating lamp with a wavelength of 0.
The properties of the outward Ca(2+)-dependent K+ current (KCa) were investigated in single smooth muscle cells (SMCs) isolated from epididymal part of the rat vas deferens (RVD) using amphotericin B perforated patch-clamp technique. The complex kinetic of the net outward current elicited by positive voltage steps from -80 mV to +40 mV suggested the presence of several components of this current. KCa current was separated from the net outward current by removal of Ca2+ from the external solution.
View Article and Find Full Text PDFTransfer factor (TF) of immune reactivity (10(-5) - 10(-3) mg/ml) to diphtheria-tetanus anatoxin modulates slow waves and spontaneous contractile activity of non-atropinized smooth muscle stripes (SMS) of guinea-pig taenia coli. TF (10(-4) mg/ml) transforms slow waves into stable depolarization and tonic contraction. After SMS atropinization, the substance acts in the same way.
View Article and Find Full Text PDFThe G-protein-dependent intracellular signal cascades of excitation in longitudinal and circular intestinal smooth muscles (SM) are compared and summarized in the present review. The key mechanism of excitation in longitudinal SM is an activation of electro-mechanical coupling, in that G-proteins, phospholipase A2, arachidonic acid, membrane-bound cyclic adenosine diphosphoribose and Ca2+ are involved. We observed the role of arachidonic acid-activated chorine and voltage-dependent Ca2+ -channels (L-type) in Ca2+ mobilization in these muscle cells.
View Article and Find Full Text PDFImmune-active substance of Staphylococcus aureus, cell-bound protein A (CBPA), enhances the acetylcholine- or hyperpotassium (K+) Krebs solution-evoked excitation in Taenia coli smooth muscles. CBPA increases caffeine- and carbachole-evoked Ca2+ signals in smooth muscle cells suspension, loaded with indo-1, and also caffeine- and acetylcholine-evoked contraction in smooth muscles slices. Against a background of CBPA-suppressed action of sodium nitroprusside, ATP evokes the membrane depolarization.
View Article and Find Full Text PDFThe mechanisms of bacterial substances (protein A, peptidoglican Staphylococcus aureus), bacterium toxins (St. aureus, Corynebacterium diphtheriae, Shigella dysenteriae, Clostridium botulinum, Clostridium tetani, Vibrio choleral), transfer factor of immune reactivity to Staphylococcus aureus upon the key link (acetylcholine-, ATP-, inositol-1,4,5-triphosphate-, ryanodin-sensitive receptors, G-proteins, Ca2+, K(+)-transporting systems, second messengers) in the chain of signal conduction of excitatory and inhibitory agonists in excitable cells were examined. The action of these immune-active substances upon contractile proteins ATP-ase activity and protein synthesis was also discussed.
View Article and Find Full Text PDFCell-bound protein A (CBPA), an immune-active substance of Staphylococcus aureus was ascertained to depolarize membrane of taenia coli smooth muscle (SM) cells, depress ATP inhibiting action (or uridinetriphosphate (UTP)) and sodium nitroprusside (SNP). ATP or UTP-induced membrane hyperpolarization increased during first minutes of CBPA exposure. Bacterial substance enhanced and then inhibited fast component of nicotine-induced relaxation of histamine-activated smooth muscles.
View Article and Find Full Text PDFThe carbachol-evoked inward cationic current in guinea-pig ileum smooth muscle cells is comprised of three types nonselective cationic channels (NSCC) with small (10 +/- 2 pS), medium (56 +/- 8pS) and large (135 +/- 14 pS) unitary conductance. All three types of NSCC could be activated by external application of carbachol as well as by internal application of GTPgS. It was found that behavior of carbachol- and GTPgammaS-evoked whole-cell current is mainly determined by the properties of medium conductance channels.
View Article and Find Full Text PDFGen Physiol Biophys
June 2003
The effects of H2O2 on electrical and mechanical activity of the longitudinal layer from the guinea-pig ileum were studied using sucrose-gap technique and the influence of H2O2 on ionic current was investigated in single smooth muscle cells by the patch-clamp method. In most of the preparations tested, the spontaneous activity observed was composed of slow waves with superimposed action potentials (APs). Both were resistant to tetrodotoxin and atropine.
View Article and Find Full Text PDFVoltage-gated components of the outward current in single smooth muscle cells isolated from the epididymal part of the rat vas deferens were studied using amphotericin B perforated patch-clamp techniques. The complex kinetics of the net outward current elicited by positive voltage steps from -80 mV to +40 mV suggested the presence of several components. Bath application of 200 nM charybdotoxin, a potent blocker of large-conductance, Ca(2+)-dependent K(+) channels (BK(Ca)), reduced the current amplitude significantly.
View Article and Find Full Text PDFIt has been shown that Transfer factor (TF) to Staphilococcus aureus antigens blocked ATP-induced component of the inhibitory junction potential in taenia coli smooth muscle from guinea-pig, and converted an inhibitory action of exogenous ATP into an exciting one (instead of the hyperpolarization of the smooth muscle, TF induced its depolarization). TF at 10-6 mg/ml converted the relaxing effects of sodium nitroprusside (nitric oxide donor) into exciting ones in smooth muscle strips. Higher concentrations (10-5-10-3 mg/ml) of TF slightly amplified the relaxing effect of sodium nitroprusside.
View Article and Find Full Text PDFFiziol Zh (1994)
October 2001
Whole-cell currents in single smooth muscle cells freshly isolated from the rat tail artery have been studied using patch-clamp recordings techniques. Outward current evoked by depolarizing steps from -70 mV consisted of the initial fast and subsequent sustained components. The former was inhibited by 10 mM nifedipine and Ca(2+)-free solution application whereas the latter decreased by only 16% under these conditions.
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