Intelligent surgical planning for automatic reconstruction of orbital blowout fracture using a prior adversarial generative network.

Orbital blowout fracture (OBF) is a disease that can result in herniation of orbital soft tissue, enophthalmos, and even severe visual dysfunction. Given the complex and diverse types of orbital wall fractures, reconstructing the orbital wall presents a significant challenge in OBF repair surgery. Accurate surgical planning is crucial in addressing this issue.

Deep learning-based automatic segmentation of bone graft material after maxillary sinus augmentation.

Objectives: To investigate the accuracy and reliability of deep learning in automatic graft material segmentation after maxillary sinus augmentation (SA) from cone-beam computed tomography (CBCT) images.

Materials And Methods: One hundred paired CBCT scans (a preoperative scan and a postoperative scan) were collected and randomly allocated to training (n = 82) and testing (n = 18) subsets. The ground truths of graft materials were labeled by three observers together (two experienced surgeons and a computer engineer).

Acetylation in pathogenesis: Revealing emerging mechanisms and therapeutic prospects.

Protein acetylation modifications play a central and pivotal role in a myriad of biological processes, spanning cellular metabolism, proliferation, differentiation, apoptosis, and beyond, by effectively reshaping protein structure and function. The metabolic state of cells is intricately connected to epigenetic modifications, which in turn influence chromatin status and gene expression patterns. Notably, pathological alterations in protein acetylation modifications are frequently observed in diseases such as metabolic syndrome, cardiovascular disorders, and cancer.

Adverse Effects of Prenatal Exposure to Oxidized Black Carbon Particles on the Reproductive System of Male Mice.

Ambient black carbon (BC), a main constituent of atmospheric particulate matter (PM), is a primary particle that is mainly generated by the incomplete combustion of fossil fuel and biomass burning. BC has been identified as a potential health risk via exposure. However, the adverse effects of exposure to BC on the male reproductive system remain unclear.

Lethal and Sublethal Toxicity of Beta-Carboline Alkaloids from (L.) against Larvae (Diptera: Culicidae).

Plant-derived agents are powerful bio-pesticides for the eco-friendly control of mosquito vectors and other blood-sucking arthropods. The larval toxicity of beta-carboline alkaloids against the Asian tiger mosquito, (Skuse) (Diptera: Culicidae), was investigated under laboratory conditions. The total alkaloid extracts (TAEs) and beta-carboline alkaloids (harmaline, harmine, harmalol, and harman) from seeds were isolated and tested in this bioassay.

AgNPs reduce reproductive capability of female mouse for their toxic effects on mouse early embryo development.

Silver nanoparticles (AgNPs) are widely applied in the field of personal protection for their powerful toxic effects on cells, and recently, a new type of vaginal gel with AgNPs is used to protect the female reproductive tract from microbes and viruses. However, a high risk of AgNPs to the fetus and the underlying mechanism of AgNPs to interfere in embryo development still remain unclear. Thus, this study investigated the impact of two drugs of vaginal gel with AgNPs on reproductive capability of the female mouse by animal experiment.

AgNPs reduce reproductive capability of female mouse for their toxic effects on mouse early embryo development.

Silver nanoparticles (AgNPs) are widely applied in the field of personal protection for their powerful toxic effects on cells, and recently, a new type of vaginal gel with AgNPs is used to protect the female reproductive tract from microbes and viruses. However, a high risk of AgNPs to the fetus and the underlying mechanism of AgNPs to interfere in embryo development still remain unclear. Thus, this study investigated the impact of two drugs of vaginal gel with AgNPs on reproductive capability of the female mouse by animal experiment.

Low-dose combined exposure of carboxylated black carbon and heavy metal lead induced potentiation of oxidative stress, DNA damage, inflammation, and apoptosis in BEAS-2B cells.

Black carbon (BC) and heavy metal lead (Pb), as typical components of atmospheric PM, have been shown to cause a variety of adverse health effects. However, co-exposure to BC and Pb may induce pulmonary damage by aggravating toxicity via an unknown mechanism. This study aimed to investigate the combined toxicity of carboxylated black carbon (c-BC) and lead acetate (Pb) on human bronchial epithelial cells (BEAS-2B) at the no-observed-adverse-effect level (NOAEL).

In vitro and in vivo toxic effects and inflammatory responses induced by carboxylated black carbon-lead complex exposure.

Black carbon (BC) is a key component of atmospheric fine particulate matter (PM) and it tends to adsorb various pollutants (e.g., heavy metals and organics) during atmospheric transport.

Insights into the binding behavior of bovine serum albumin to black carbon nanoparticles and induced cytotoxicity.

Black carbon (BC) is a main component of particulate matter (PM). Due to their small size (<100nm), inhaled ultrafine BC nanoparticles may penetrate the lung alveoli, where they interact with surfactant proteins and lipids, causing more serious damage to human health. Here, BC was analyzed to investigate the binding mechanism of its interaction with protein and induction of cytotoxicity changes.

[Avian diversity and bird strike risk at Fuyang Airport].

From June 2008 to January 2010, a survey of avian communities was conducted in five habitats (grassland, farmland, town, wetland, and woodland) at Fuyang Airport and its surrounding areas, with the diversity indices in different seasons and different habitats analyzed. A total of 122 avian species belonging to 15 orders and 40 families were recorded. At Fuyang Airport, the avian species number was significantly higher in summer and autumn than in winter and spring, the avian density was the highest in autumn, and the Shannon diversity index and Pielou evenness index were the highest in summer.