Publications by authors named "Shuangjuan Liu"

The gram-negative bacterium (VC) is divided into multiple serogroups, with groups O1 and O139 responsible for cholera. Conversely, belonging to the non-O1/non-O139 group (NOVC) does not produce cholera-causing toxins. Insufficient understanding of the frequency of NOVC causes fear during the early detection phase.

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Article Synopsis
  • - This study utilized Mendelian randomization to explore the potential link between systemic lupus erythematosus (SLE) and seven psychiatric disorders, due to prior observational studies suggesting such a connection.
  • - Genetic data from over 23,000 individuals were analyzed, revealing that SLE is significantly associated with an increased risk of generalized anxiety disorder (GAD) and schizophrenia (SCZ), while no causal relationships were found for other psychiatric disorders.
  • - The findings indicate that SLE could lead to a higher risk of GAD and SCZ in a European demographic; however, further research is recommended to better understand these relationships, especially considering genetic diversity across different populations.
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Background: Observational studies have suggested that COVID-19 increases the prevalence of psychiatric disorders, but the results of such studies are inconsistent. This study aims to investigate the association between COVID-19 and the risk of psychiatric disorders using Mendelian randomization (MR) analysis.

Methods: We used summary statistics from COVID-19 Host Genetics Initiative genome-wide association study (GWAS) of COVID-19 involving 2,586,691 participants from European ancestry.

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Introduction: Observational studies suggested that diabetes mellitus [type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM)], multiple sclerosis (MS), and migraine are associated with Alzheimer's disease (AD). However, the causal link has not been fully elucidated. Thus, we aim to assess the causal link between T1DM, T2DM, MS, and migraine with the risk of AD using a two-sample Mendelian randomization (MR) study.

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