Publications by authors named "Shuang-wu Liang"
Article Synopsis
- The study investigates how introducing the CXCR4 gene to human breast adipose-derived stem cells (HBASCs) can enhance the survival and neovascularization of autologous fat tissue transplants in nude mice, addressing issues like fat resorption and calcification.
- Results show that transplants mixed with CXCR4-transfected HBASCs achieved a significantly higher volume survival rate (79.5%) compared to the control group (28.3%) and even untransfected HBASCs (67.2%).
- The research highlights the potential of using genetically modified HBASCs to improve the long-term success of fat tissue grafts, suggesting that CXCR4 plays a crucial role in recruiting cells needed for blood vessel formation
Article Synopsis
- Human adipose-derived stem cells from breast tissue (hbASCs) were isolated and characterized to explore their potential in stem cell research and therapy.
- These hbASCs showed specific surface markers relevant for their classification and were capable of differentiating into various cell types like adipocytes and osteocytes.
- Additionally, using activated autologous platelet-rich plasma (PRP) significantly enhanced the hbASCs' growth and their conversion into mammary gland-like epithelial cells, suggesting a promising avenue for breast reconstruction applications.
Objective: To investigate the effect of rabbit saphenous and sciatic nerve homogenates on the proliferation and calcification of rabbit osteoblasts in vitro.
Method: The saphenous nerves (sensory nerves) and the muscular branches of the sciatic nerve (motor nerve) were collected from 48 New Zealand white rabbits to prepare the nerve tissue homogenates. Bone marrow mesenchymal stem cells (MSCs) were isolated from the rabbits and cultured in vitro, and after 14 days of routine osteogenic induction, the resultant osteoblasts were identified by immunohistochemistry, alkaline phosphatase (ALP) and Alizarin red S staining.