Zhongguo Ying Yong Sheng Li Xue Za Zhi
September 2020
To investigate the effects of Ganmai Dazao Tang on behavior and monoamine neurotransmitters in rats with depression, and to explore its potential mechanism from synaptic structure. Sixty SD rats were randomly divided into 5 groups: normal control group, model group, fluoxetine group (10.8 mg/kg), Ganmai Dazao Tang high and low dose group (9.
View Article and Find Full Text PDFZhongguo Ying Yong Sheng Li Xue Za Zhi
July 2020
Objective: To investigate the effects of modified Xiaoyao San on TLR4/NF-κB pathway in hippocampal microglia of LPS-induced depression model rats, and to explore its antidepressant mechanism.
Methods: SD rats were randomly divided into control, model, fluoxetine (10 mg·kg), low and high dose of modified Xiaoyao San (3.64, 7.