Constructing a predictive model based on peripheral blood signs to differentiate infectious mononucleosis from chronic active EBV infection.

Objective: To develop a prediction model based on peripheral blood signs to distinguish between infectious mononucleosis and chronic active EBV infection.

Methods: Retrospective data was collected for 60 patients with IM (IM group) and 20 patients with CAEBV infection (CAEBV group) who were hospitalized and diagnosed at the General Hospital of Tianjin Medical University between December 2018 and September 2022. The analyses used were univariate and LASSO (least absolute shrinkage and selection operator) logistic regression.

[Changes of serum BAFF and IL-21 levels in patients with systemic lupus erythematosus and their clinical significance].

Aim: To investigate the changes of serum BAFF and IL-21 levels in the patients with systemic lupus erythematosus (SLE) and explore their clinical significance.

Methods: The serum levels of BAFF and IL-21 were detected by enzyme-linked immunosorbent assay (ELISA).

Results: The levels of serum BAFF and IL-21 in the patients with SLE were obviously higher than those in healthy control group.

[Serum IL-21 level in patients with primary Sjogren's syndrome and clinical significance of IL-21].

Aim: To investigate the relation between the change of serum IL-21 level and other laboratory indexes by detecting serum IL-21 level from patients with primary Sjogren's syndrome (pSS) and explore the role of IL-21 in pSS.

Methods: The level of serum IL-21 from 40 pSS patients diagnosed according to 2002 revised international classification criteria for pSS and 30 healthy persons were detected by enzyme-linked immunosorbent assay(ELISA) respectively. Meanwhile, FT3, FT4, TSH, TgAb, TPOAb were detected by Immunochemiluminescent technique.