S-S Bond Strategy at Sulfide Heterointerface: Reversing Charge Transfer and Constructing Hydrogen Spillover for Boosted Hydrogen Evolution.

Developing efficient electrocatalyst in sulfides for hydrogen evolution reaction (HER) still poses challenges due to the lack of understanding the role of sulfide heterointerface. Here, we report a sulfide heterostructure RuS/NbS, which is composed of 3R-type NbS loaded by amorphous RuS nanoparticles with S-S bonds formed at the interface. As HER electrocatalyst, the RuS/NbS shows remarkable low overpotential of 38 mV to drive a current density of 10 mA cm in acid, and also low Tafel slope of 51.

Spherical fluorinated covalent organic polymer for highly efficient and selective extraction of fipronil and its metabolites in soil.

Covalent organic polymers (COPs) have garnered considerable attention as promising adsorbents of online solid phase extraction (online SPE). Morphology modulation provides an appealing solution to enhance adsorption efficiency and reduce back-pressure in the absorbent. However, the synthesis of COPs with regular geometric shapes and specific adsorption selectivity remains challenging.

An iRGD peptide conjugated heparin nanocarrier for gastric cancer therapy.

The -diamminedichloroplatinum(ii) (DDP, cisplatin) is an important antitumor drug for the therapy of gastric cancer in clinics, but it is limited by its nonspecific tissue distribution and severe side effects. Here, an integrin targeted drug delivery system iRGD-heparin nanocarrier (iHP) was successfully synthesized. The iHP has several unique properties.

microRNA-129-5p suppresses Adriamycin resistance in breast cancer by targeting SOX2.

Adriamycin resistance is closely related to therapeutic efficacy in breast cancer patients and their prognosis. Increasing evidence has suggested that miRNA functions in Adriamycin resistance in various types of cancer. microRNA-129-5p (miR-129-5p) has been considered a tumor-suppressive miRNA in several cancers, but its potential role in Adriamycin resistance in breast cancer has not been fully elucidate.

Preliminary studies on palladium nanoparticle as a novel label for DNA microarray and their corresponding detection.

This paper firstly describes the preliminary results achieved by using palladium nanoparticle (Pd NP) as a novel label for the detection of DNA hybridization in DNA microarray. And two signal amplification procedures based on "the silver staining" or "the cobalt staining" are presented during above analysis. The results show that the label Pd NP-ssDNA (target) (single strand DNA(target)) performs high single base pair mismatch-discrimination capability.

Preparation of carboxyl group-modified palladium nanoparticles in an aqueous solution and their conjugation with DNA.

The use of nanomaterials in biomolecular labeling and their corresponding detection has been attracting much attention, recently. There are currently very few studies on palladium nanoparticles (Pd NPs) due to their lack of appropriate surface functionalities for conjugation with DNA. In this paper, we thus firstly present an approach to prepare carboxyl group-modified Pd NPs (with an average size of 6 nm) by the use of 11-mercaptoundecanoic acid (MUDA) as a stabilizer in the aqueous solution.