Clinical patterns and the evolution of relapsing polychondritis based on organ involvement: a Chinese retrospective cohort study.

Background: Relapsing polychondritis (RPC) is a rare autoimmune disease and its early diagnosis remains challenging. Defining the clinical patterns and disease course may help early recognition of RPC.

Results: Sixty-six males and 60 females were included in this study.

Analysis of molecular pathological factors of unfavorable prognosis for young cervical cancer patients.

Unlabelled: The aim of this study was to explore the molecular pathological characteristics of cervical cancer in women aged below 35, disclose the factors that indicate the unfavorable prognosis, and provide some useful targets for improving therapeutic outcome.

Patients And Methods: 64 cases of pathological data originating from cervical cancer patients aged below 35 served as the study group to perform a retrospective research, and pathological data from 90 cases of cervical cancer patients beyond age 35, who underwent treatment during the same time, were selected at random as the reference group. Immunohistochemistry and quantified image analysis were utilized to detect synchronously the protein expression difference of survivin and p27 between the 2 groups.