Surface-enhanced Raman scattering (SERS) has emerged as a powerful tool for contamination detection. Fabricating efficient nanostructures with hotspots for signal enhancement and concentrating diluted target analyte molecules to the hotspots are critical for ultrasensitive SERS detection, which generally requires advanced instruments and intricate manipulations. Herein, we report a simple, low-cost, and high-efficiency paper device that can simultaneously concentrate the analytes and generate SERS hotspots rapidly with the assistance of laser-induced thermophoresis.
View Article and Find Full Text PDFAnion exchange resin (AER) adsorption is an effective technology for the removal of per- and polyfluoroalkyl substances (PFAS) from wastewater. However, existing AERs with tributylamine functional groups have poor adsorption selectivity for perfluorinated carboxylic acids (PFCAs) and 6:2 fluorotelomer sulfonate (6:2 FTS), and the structure-selectivity relationship is still unclear. In this study, several novel gel AERs with long-chain amine groups were prepared.
View Article and Find Full Text PDFPerovskite nanocrystals (PNCs) are endowed with extraordinary photophysical properties such as wide absorption spectra, high quantum yield, and narrow emission bands. However, the inherent shortcomings, especially the instability in polar solvents and water incompatibility, have hindered their application as probes in chem/bio sensing. In this review, we give a fundamental understanding of the challenges when using PNCs for chem/bio sensing and summarize recent progress in this area, including the application of PNCs in various sensors and the corresponding strategies to maintain their structural integrity.
View Article and Find Full Text PDFObjective: Decompressive craniectomy (DC) is widely used to treat intracranial hypertension following severe head injury. However, impairments of cerebrospinal fluid (CSF) hydrodynamics such as hydrocephalus and subdural effusion are common complications that occur after DC. Therefore, monitoring of intracranial pressure is a staple of neurocritical care post-DC.
View Article and Find Full Text PDFObjective: The choice of the most appropriate therapeutic approach for a diagnosed papillary thyroid microcarcinoma (PTMC) remains controversial. The present study aimed to evaluate the efficacy of microwave ablation (MWA) for unifocal PTMC with a diameter of ≤0.6 cm.
View Article and Find Full Text PDFWesternization of dietary habits increases lipid intake and is responsible for increased numbers of patients with atherosclerotic diseases. Niemann-Pick C1-Like 1 (NPC1L1)-a cholesterol importer-plays a crucial role in dietary cholesterol absorption in the intestine and is closely associated with several lipid-related diseases, including atherosclerosis. NPC1L1 is highly expressed in the liver and intestine in humans, whereas NPC1L1 expression is low in the rodent liver.
View Article and Find Full Text PDFZhonghua Jie He He Hu Xi Za Zhi
December 2011
Background And Objective: A single infective acute exacerbation of chronic bronchitis (AECB) has a sustained effect on health status. Although a number of clinical investigations have demonstrated the efficacy of antibiotics in AECB, increased bacterial resistance has caused concern about the efficacy of currently available antibiotic therapies. This subanalysis of a global noninterventional study aimed to evaluate the impact of AECB on the patient and the community and the effectiveness and safety of a treatment with moxifloxacin (MXF) tablets in daily life clinical practice in China.
View Article and Find Full Text PDFZhonghua Nei Ke Za Zhi
August 2008
Objective: To evaluate the impact of the asthma education and management model developed by Peking University People's Hospital on the level of asthma control.
Methods: Trained respiratory physicians from 6 large teaching hospitals in the urban districts of Beijing conducted a successive questionnaire survey in the form of face-to-face interviews with adult asthma patients attending their respective clinics. The results were used to compare the levels of asthma control between patients who were administered "three-in-one" asthma education and management (education group) and those who were not (control group).
Zhonghua Jie He He Hu Xi Za Zhi
November 2006
Objective: To evaluate the impact of an asthmatic patient education program on asthma control and quality of life.
Methods: The program, which consisted of a special clinic for asthma, an asthma education center and the Asthmatic Patients Association, was carried out in Peking University People's Hospital. Interview-administered questionnaire of two groups of adult outpatients between Apr.