Relationship between triglyceride-glucose index and cognitive function among community-dwelling older adults: a population-based cohort study.

Background: The global increase in the aging population presents considerable challenges, particularly regarding cognitive impairment, a major concern for public health. This study investigates the association between the triglyceride-glucose (TyG) index, a measure of insulin resistance, and the risk of cognitive impairment in the elderly.

Methods: This prospective cohort study enrolled 2,959 participants aged 65 and above from the 2015 and 2020 waves of the China Health and Retirement Longitudinal Study (CHARLS).

Graph-Based Restricted and Arbitrary Switching for Switched Positive Systems via a Weak CLCLF.

This article studies the stability problem of discrete-time switched positive linear systems (SPLSs) with marginally stable subsystems. Based on the weak common linear copositive Lyapunov function (weak CLCLF) approach, the switching property and the state component property are combined to ensure the asymptotic stability of SPLSs under three types of switching signals. First, considering the transfer-restricted switching signal described by the switching digraph, novel cycle-dependent joint path conditions are proposed in combination with state component digraphs.

Microstructure Evolution Mechanism of Ultra-Thin Dual Phase Magnesium-Lithium Alloy during Asymmetric Warm Rolling.

Magnesium-lithium alloy is the lightest metal alloy material so far, and the ultra-thin plate is also one of the main trends in the future development of Mg-Li alloy. In order to explore how to prepare LZ91 ultra-thin Mg-Li alloy, this topic adopts the combination of the finite element method (FEM) and visco-plastic self-consistent (VPSC) calculation, electron back-scattered diffraction (EBSD) and tensile experiment, and uses the asymmetric warm rolling process to realize the processing of ultra-thin LZ91 Mg-Li alloy plate with a thickness of 0.25 mm.

Relative Fuzzy Rough Approximations for Feature Selection and Classification.

Fuzzy rough set (FRS) theory is generally used to measure the uncertainty of data. However, this theory cannot work well when the class density of a data distribution differs greatly. In this work, a relative distance measure is first proposed to fit the mentioned data distribution.

Analysis of Evolution, Expression and Genetic Transformation of TCP Transcription Factors in Blueberry Reveal That Negatively Regulates the Release of Flower Bud Dormancy.

Plant-specific TEOSINTE BRANCHED 1, CYCLOIDEA, PROLIFERATING CELL FACTORS (TCP) transcription factors have versatile functions in plant growth, development and response to environmental stress. Despite blueberry's value as an important fruit crop, the TCP gene family has not been systematically studied in this plant. The current study identified blueberry TCP genes () using genomic data from the tetraploid blueberry variety 'Draper'; a total of 62 genes were obtained.

[Clinical and genetic analysis of a Chinese pedigree affected with Smith-Lemli-Opitz syndrome].

Objective: To explore the clinical phenotype and pathogenic variants in a Chinese pedigree affected with Smith-Lemli-Opitz syndrome.

Methods: Peripheral blood samples were collected from five members, including two affected ones, from the pedigree for the extraction of genomic DNA. Whole exome sequencing was carried out, and candidate variants were verified by Sanger sequencing as well as reverse transcription sequencing at the RNA level.

[Prospective study of ketogenic diet in treatment of children with global developmental delay].

Objective: To study the effect of ketogenic diet (KD) on neurobehavioral development, emotional and social behaviors, and life ability in children with global developmental delay (GDD).

Methods: A prospective case-control study was performed for hospitalized children with GDD, who were randomly divided into KD treatment group (n=40) and conventional treatment group (n=37). The children in both groups were given comprehensive rehabilitation training, and those in the KD treatment group were given modified Atkins diet in addition to the comprehensive rehabilitation training.

Data-Distribution-Aware Fuzzy Rough Set Model and its Application to Robust Classification.

Fuzzy rough sets (FRSs) are considered to be a powerful model for analyzing uncertainty in data. This model encapsulates two types of uncertainty: 1) fuzziness coming from the vagueness in human concept formation and 2) roughness rooted in the granulation coming with human cognition. The rough set theory has been widely applied to feature selection, attribute reduction, and classification.

Development and application of an oligonucleotide microarray for the detection of food-borne bacterial pathogens.

The rapid and accurate detection and identification of food-borne pathogenic bacteria is critical for food safety. In this paper, we describe a rapid (<4 h) high-throughput detection and identification system that uses universal polymerase chain reaction (PCR) primers to amplify a variable region of bacterial the 16S rRNA gene, followed by reverse hybridization of the products to species-specific oligonucleotide probes on a chip. This procedure was successful in discriminating 204 strains of bacteria from pure culture belonging to 13 genera of bacteria.

The design and application of DNA chips for early detection of SARS-CoV from clinical samples.

Background: SARS coronavirus has been identified as the cause of severe acute respiratory syndrome (SARS). Few tests allow confirmation or exclusion of SARS within the first few days of infection. A gene chip is a useful tool for the study of microbial infections mainly for its capability of performing multi-target analysis in a single test.

Response of gene expression in Saccharomyces cerevisiae to amphotericin B and nystatin measured by microarrays.

The response of the yeast Saccharomyces cerevisiae to two polyene antibiotics, amphotericin B and nystatin, was studied by genomic expression profiling. The two agents produced highly similar expression pattern changes, which was consistent with their known identical mechanisms of action on cell membranes. Detailed analysis was focused on the amphotericin B-treated sample in this study.