Morphology optimization pre-aggregation and miscibility matching in PM6:L8-BO ternary organic solar cells.

To elucidate the mechanism by which pre-aggregation and miscibility matching govern the active layer morphology in non-fullerene organic solar cells, chloroform (CF) and -xylene (OX) were used as solvents, while D18 and N2200 were incorporated as third components into the PM6:L8-BO system. The incorporation of D18 enhanced device performance, whereas the addition of N2200 reduced device performance. Based on surface energy analysis, the free energies of pure components and binary blends in different solvents were calculated, showing that the Gibbs free energies of D18, PM6 and L8-BO exhibited better pre-aggregation matching.

Quaternary Ammonium Salt-Based Intrinsic Antibacterial Polyurethanes: Optimizing the Antibacterial Activity via Cationic Main- or Side-Chain Design in Hard Segments.

Thermoplastic polyurethanes (TPUs) are one of the most appealing materials with extensive applications in biomedical fields due to their versatile mechanical properties and excellent biocompatibility. In response to the escalating challenges of bacterial infections, it is desirable to obtain TPUs with intrinsic antibacterial activity, particularly for application in biomedical devices and public places. Herein, a cationic main-/side-chain structure regulation strategy in the TPU hard segment was adopted to introduce and optimize the antibacterial activity.

The relationship between NLR, LDL-C/HDL-C, NHR and coronary artery disease.

Objective: Chronic inflammation and dyslipidemia are key risk factors for atherosclerotic cardiovascular diseases. We retrospectively explored the association between the neutrophil to lymphocyte ratio (NLR), the ratio of low-density lipoprotein cholesterol (LDL-C) to high-density lipoprotein cholesterol (HDL-C), and the neutrophil to HDL-C ratio (NHR), and the severity of coronary lesions in patients with acute coronary syndrome (ACS).

Method: In June 2023, we selected 1210 patients who were diagnosed with ACS based on chest pain from January 2017 to December 2022.

Fabrication of Bioresorbable Barrier Membranes from Gelatin/Poly(4-Hydroxybutyrate) (P4HB).

Dental implant surgery is a procedure that replaces damaged or missing teeth with an artificial implant. During this procedure, guided bone regeneration (GBR) membranes are commonly used to inhibit the migration of epithelium and GBR at the surgical sites. Due to its biodegradability, good biocompatibility, and unique biological properties, gelatin (GT) is considered a suitable candidate for guiding periodontal tissue regeneration.

A Case of Severe Rhabdomyolysis, Acute Myocardial Damage and Multi-Organ Dysfunction Syndrome in a Patient with Novel Coronavirus Pneumonia.

In recent years, healthcare systems worldwide have faced the challenge of the severe COVID-19 pandemic. However, cases of severe rhabdomyolysis, acute myocardial damage, and multiple organ dysfunction syndrome (MODS) caused by COVID-19 are currently rare. This report presents a case of severe rhabdomyolysis, acute myocardial damage, and MODS caused by COVID-19.

On the application of Marcus-Hush theory to small polaron chemical dynamics in oxides: its relationship to the Holstein model and the importance of lattice-orbital symmetries.

The chemical dynamics of small polaron hopping within oxides is often interpreted through two-site variations on Marcus-Hush theory, while from a physics perspective small polaron hopping is more often approached from Holstein's solid-state formalism. Here we seek to provide a chemically oriented viewpoint, focusing on small polaron hopping in oxides, concerning these two phenomenological frameworks by employing both tight-binding modelling and first-principles calculations. First, within a semiclassical approach the Marcus-Hush relations are overviewed as a two-site reduction of Holstein's model.

Fabrication of Oleophilic Polypeptide Nanoparticle from Complexing of Cross-Linked Epsilon-poly-l-lysine with Docusate Sodium for Preparation of Bactericidal Thermoplastic Polyurethanes.

Thermoplastic polyurethanes (TPUs) are extensively utilized in the biomedical field due to their exceptional mechanical properties and biocompatibility. However, the lack of antibacterial activity limits their application ranges. Nanoscopic particle-based additives with inherent antibacterial characteristics are regarded as promising strategies to prevent biomaterials-associated infection.

Case report: Ultrasound-guided needle knife technique for carpal ligament release in carpal tunnel syndrome treatment.

Carpal tunnel syndrome (CTS) is a common peripheral neuropathy of the hand, mainly manifesting as sensory disturbances, motor dysfunctions, and pain in the fingers and hand. The pathogenesis of the disease is associated with fibrosis of the transverse carpal ligament in the carpal tunnel, which compresses median nerve. In our case, we demonstrate an ultrasound-guided needle knife technique to treat CTS.

Hyperbranched Poly-L-Lysine-Based Water-Insoluble Complexes as Antibacterial Agents with Efficient Antibacterial Activity And Cytocompatibility.

Despite the advances in technology, bacterial infection associated with biomedical devices is still one of the most challenging issues in clinical practice. Incorporation of antimicrobial agents is regarded as an efficient way to combat medical device associated infectious. However, most of antimicrobial agents have high toxicity to host cells.

Multifunctional Fluorinated Lubricant-Infused Poly(4-Hydroxybutyrate) (P4HB) Membranes for Full-Thickness Abdominal Wall Defect Repair.

Abdominal wall defect caused by surgical trauma, congenital rupture, or tumor resection may result in hernia formation or even death. Tension-free abdominal wall defect repair by using patches is the gold standard to solve such problems. However, adhesions following patch implantation remain one of the most challenging issues in surgical practice.

Ultra-high performance humidity sensor enabled by a self-assembled CuO/TiCT MXene.

An ultra-high performance humidity sensor based on a CuO/TiCT MXene has been investigated in this work. The moisture-sensitive material was fabricated by a self-assembly method. The morphology and nanostructure of the fabricated CuO/TiCT composites were characterized by scanning electron microscopy, transmission electron microscopy, X-ray diffraction, and X-ray photoelectron spectra.

Collaborative Enhancement of Humidity Sensing Performance by KCl-Doped CuO/SnO p-n Heterostructures for Monitoring Human Activities.

In this study, a high-performance humidity sensor based on KCl-doped CuO/SnO p-n heterostructures was fabricated by a ball milling-roasting method. The morphology and nanostructure of the fabricated KCl-CuO/SnO composite were characterized by scanning electron microscopy, X-ray diffraction, transmission electron microscopy, X-ray photoelectron spectroscopy, and nitrogen sorption analysis. The results showed that the humidity sensor had a high sensitivity of 194 kΩ/%RH, short response and recovery times of 1.

First-principles redox energy estimates under the condition of satisfying the general form of Koopmans' theorem: An atomistic study of aqueous iron.

In this work, we explore the relative accuracy to which a hybrid functional, in the context of density functional theory, may predict redox properties under the constraint of satisfying the general form of Koopmans' theorem. Taking aqueous iron as our model system within the framework of first-principles molecular dynamics, direct comparison between computed single-particle energies and experimental ionization data is assessed by both (1) tuning the degree of hybrid exchange, to satisfy the general form of Koopmans' theorem, and (2) ensuring the application of finite-size corrections. These finite-size corrections are benchmarked through classical molecular dynamics calculations, extended to large atomic ensembles, for which good convergence is obtained in the large supercell limit.

[Correlation between neutrophil/lymphocyte ratio combined with low-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio and severity of coronary artery disease in patients with acute coronary syndrome].

Objective: To investigate the correlation between neutrophil/lymphocyte ratio (NLR) combined with low-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio (LDL-C/HDL-C) and severity of coronary lesions in patients with acute coronary syndrome (ACS).

Methods: Patients who were diagnosed with ACS due to chest pain and received emergency coronary angiography in the First Affiliated Hospital of University of Science and Technology of China and the Affiliated Hospital of Anhui Medical University from January 2017 to June 2020 were enrolled in the final analysis. The data of gender, age, body mass index (BMI), past history, emergency blood routine indicators [neutrophil (NEU), lymphocyte (LYM), monocyte (MON), eosinophil (EOS), basophil (BAS), red blood cell (RBC), mean corpuscular volume (MCV), blood red cell distribution width (RDW), mean platelet volume (MPV), platelet volume distribution width (PDW)], blood lipid index [triglyceride (TG), total cholesterol (TC), HDL-C, LDL-C, very low-density lipoprotein cholesterol (VLDL-C)], and coronary angiography were collected.

Bioactive Poly(4-hydroxybutyrate)/Poly(ethylene glycol) Fibrous Dressings Incorporated with Zinc Oxide Nanoparticles for Efficient Antibacterial Therapy and Rapid Clotting.

Antibacterial and hemostatic properties are of great importance to wound dressing in treating trauma. Poly(4-hydroxybutyrate) (P4HB), an U.S.

Slippery 3-dimensional porous bioabsorbable membranes with anti-adhesion and bactericidal properties as substitute for vaseline gauze.

Vaseline gauze is a common type of wound dressing that consist of absorbent gauze impregnated with white petrolatum. It has excellent anti-adhesive property which can reduce trauma during dressing changes. However, this kind of wound dressing doesn't have bacterial killing property.

Injectable Cell- and Growth Factor-Free Poly(4-hydroxybutyrate) (P4HB) Microspheres with Open Porous Structures and Great Efficiency of Promoting Bone Regeneration.

Delivering injectable microspheres in a minimally invasive way to repair complexly shaped tissue defects renders them attractive for clinical use. Especially, open porous microspheres that provide sufficient internal space for cell proliferation and nutrient diffusions can efficiently aid to completing reconstructions of tissue defects. In this work, chemically synthesized and biodegradable poly(4-hydroxybutyrate) (P4HB), which is the U.

Dual Interface Protection for High Performance and Excellent Long-Term Stability of Organic Solar Cells.

Stability is still the main barrier to the commercial application of organic solar cells (OSCs), although the maximal power conversion efficiency (PCE) value has exceeded 19%. The encapsulation technique is an effective and vital way to guarantee the long-term stabilities of OSCs, but it can only avoid the penetration of water and oxygen from the environment. Herein, we introduced a structure that provides dual interface protection by using commercially available and chemically stable polyvinylidene fluoride (PVDF) as the cathode interface protection layer working as the cathode interlayer (CIL) and poly(styrene-comethyl-methacrylate) (PS-r-PMMA) as the anode interface protection layer between the poly(3,4-ethylenedioxythiophene)/poly(styrene sulfonate) (PEDOT:PSS) and the active layer.

Bioabsorbable poly(4-hydroxybutyrate) (P4HB) fibrous membranes as a potential dermal substitute.

Dermal substitutes are indispensable for repairing large full-thickness skin defects. Only a few biomaterials for dermal substitution have been put into clinical practice. Therefore, novel artificial dermal substitutes that can meet clinical requirements are in urgent need.

Ergodic and Nonergodic Dynamics of Oxygen Vacancy Migration at the Nanoscale in Inorganic Perovskites.

Perovskites are widely utilized either as a primary component or as a substrate in which the dynamics of charged oxygen vacancy defects play an important role. Current knowledge regarding the dynamics of vacancy mobility in perovskites is solely based upon volume- and/or time-averaged measurements. This impedes our understanding of the basic physical principles governing defect migration in inorganic materials.

Electrical Stressing Induced Monolayer Vacancy Island Growth on TiSe.

To ensure practical applications of atomically thin transition metal dichalcogenides, it is essential to characterize their structural stability under external stimuli such as electric fields and currents. Using vacancy monolayer islands on TiSe surfaces as a model system, we have observed nonlinear area evolution and growth from triangular to hexagonal driven by scanning tunneling microscopy (STM) subjected electrical stressing. The observed growth dynamics represent a 2D departure from the linear area growth law expected for bulk vacancy clustering.

pH-Responsive Peptide Supramolecular Hydrogels with Antibacterial Activity.

Smart hydrogels have received increasing attention for many applications. Here, we synthesized a class of cationic peptide amphiphiles that can self-assemble into hydrogels by ring-opening polymerization (ROP) and post-modification strategy. The incorporation of cationic lysine residues suppresses the formation of fibril-like structure and further the gelation ability of the samples.

A hierarchical polymer brush coating with dual-function antibacterial capability.

Bacterial infections are problematic in many healthcare-associated devices. Antibacterial surfaces integrating the strength of bacteria repellent and bactericidal functions exhibit an encouraging efficacy in tackling this problem. Herein, a hierarchical dual-function antibacterial polymer brush coating that integrates an antifouling bottom layer with a bactericidal top layer is facilely constructed via living photograft polymerization.

A hierarchical polymer brush coating with dual-function antibacterial capability.

Bacterial infections are problematic in many healthcare-associated devices. Antibacterial surfaces integrating the strength of bacteria repellent and bactericidal functions exhibit an encouraging efficacy in tackling this problem. Herein, a hierarchical dual-function antibacterial polymer brush coating that integrates an antifouling bottom layer with a bactericidal top layer is facilely constructed via living photograft polymerization.