Sodium oligomannate disrupts the adherence of Rib bacteria to gut epithelia to block SAA-triggered Th1 inflammation in 5XFAD transgenic mice.

Sodium oligomannate (GV-971), an oligosaccharide drug approved in China for treating mild-to-moderate Alzheimer's disease (AD), was previously found to recondition the gut microbiota and limit altered peripheral Th1 immunity in AD transgenic mice. As a follow-up study, we here made advances by pinpointing a Lactobacillus murinus (L.m.

Preparation and characterization of Tobacco polysaccharides and its modulation on hyperlipidemia in high-fat-diet-induced mice.

This study aimed to investigate the structural properties of tobacco polysaccharide (TP) and its mechanism of modulating hyperlipidemia in high-fat diet-induced mice. The structural properties of TP were characterized by FT-IR, 1HNMR, SEM, AFM and thermogravimetric analysis. And the regulatory mechanism of TP on lipid metabolism was investigated in hyperlipidemia mice.

In vitro study on antioxidant and lipid-lowering activities of tobacco polysaccharides.

Tobacco polysaccharides were extracted by hot water extraction, and purified and separated using DEAE-52 cellulose chromatography columns, and three purified polysaccharide fractions, YCT-1, YCT-2, and YCT-3, were finally obtained. The physicochemical properties of the three fractions were analyzed by ultraviolet spectroscopy, high-performance liquid chromatography and high-performance gel chromatography. The in vitro antioxidant activity of tobacco polysaccharides was compared among different fractions by using DPPH radical, hydroxyl radical scavenging assay and potassium ferricyanide method.

Novel pretreatment with hydrogen peroxide enhanced microwave biochar for heavy metals adsorption: Characterization and adsorption performance.

Hydrogen peroxide (HP) was used to pretreat wheat straw (WS) for microwave biochar production at 100-600 W, the physicochemical properties of pretreated WS and biochar products as well as heavy metals adsorption performance were investigated. Results showed that HP enhanced specific surface area (SSA) and pore volume (PV) of WS, and the largest SSA (190.35 m g) and PV (0.

Microwave biochar produced with activated carbon catalyst: Characterization and adsorption of heavy metals.

Novel microwave biochar derived from wheat straw (WS) using a range of power levels, with activated carbon catalyst as microwave absorber, was produced, characterized and tested as adsorbent of three heavy metals (Pb, Cd, and Cu). The microwave biochar with the greatest specific surface area (156.09 m g) and total pore volume (0.