Diagnostic capability of 18F-PSMA PET-MRI and pelvic MRI plus bone scan in treatment-naive prostate cancer: a single-center paired validating confirmatory study.

Background: Radical prostatectomy with pelvic lymph node dissection for the treatment of high-risk localized prostate cancer (PCa) results in long-term benefits in selected patients. But insufficient sensitivity of conventional examinations which are pelvic MRI and bone scan, limits the diagnosis of bone and lymph node metastasis of PCa. This affects the surgical management strategy of a large number of patients.

Association of biopsy core number and location with pain in patients undergoing a transperineal prostate biopsy under local anaesthesia: a secondary analysis of the APROPOS trial.

Background: APROPOS was a multicentre, randomized, blinded trial focus on investigating the perineal nerve block versus the periprostatic block in pain control for men undergoing a transperineal prostate biopsy. In the analysis reported here, the authors aimed to evaluate the association of biopsy core count and location with pain outcomes in patients undergoing a transperineal prostate biopsy under local anesthesia.

Methods: APROPOS was performed at six medical centers in China.

Efficient 3D scanning measurement system based on asymmetric trinocular vision and a multi-line laser.

The laser scanning measurement system has a pivotal role in precision measurement thanks to the non-contacting and low-cost advantages, but traditional methods and systems are inadequate in terms of accuracy, efficiency, and adaptability. In this study, an efficient 3D scanning measurement system based on asymmetric trinocular vision and a multi-line laser is developed to improve the measurement performance. The system design, working principle, and 3D reconstruction method are explored, as well as the innovation of the developed system.

Perineal nerve block versus periprostatic block for patients undergoing transperineal prostate biopsy (APROPOS): a prospective, multicentre, randomised controlled study.

Background: We aimed to investigate perineal nerve block versus periprostatic block in pain control for men undergoing a transperineal prostate biopsy.

Methods: In this prospective, randomised, blinded and parallel-group trial, men in six Chinese hospitals with suspected prostate cancer were randomly assigned (1:1) at the point of local anaesthesia to receive a perineal nerve block or periprostatic block and followed by a transperineal prostate biopsy. Centres used their usual biopsy procedure.

Gross tumor volume delineation in primary prostate cancer on F-PSMA-1007 PET/MRI and Ga-PSMA-11 PET/MRI.

Background: We aimed to assess the clinical value of F-PSMA-1007 and Ga-PSMA-11 PET/MRI in the gross tumor volume (GTV) delineation of radiotherapy for prostate cancer (PCa).

Methods: Sixty-nine patients were retrospectively enrolled (57 in the F subgroup and 12 in the Ga subgroup). Three physicians delineated the GTV and tumor length by the visual method and threshold method with thresholds of 30%, 40%, 50%, and 60% SUVmax.

Robust and accurate sub-pixel extraction method of laser stripes in complex circumstances.

Line laser scanning measurement is a major area of interest within the field of 3D laser scanning measurement. Traditionally, sub-pixel extraction of laser stripes is a dominant point for line laser scanning measurement. In particular, the noise separation of laser stripe images and the accuracy of feature extraction of the laser stripe are the main challenges for sub-pixel extraction of laser stripes in complex circumstances.

A Multicenter Single-Arm Objective Performance Criteria Trial to Determine the Efficacy and Safety of High-Frequency Irreversible Electroporation as Primary Treatment for Localized Prostate Cancer: A Study Protocol.

Introduction: The classical pathway for the therapy of low- to intermediate-risk localized prostate cancer is radical prostatectomy or radiation therapy, which has shown a high incidence of complications, including erectile dysfunction, urinary incontinence, and bowel injury. An alternative pathway is to perform an ablation by some energy to the localized lesion, known as focal therapy. High-frequency irreversible electroporation (H-FIRE) is nonthermal energy that can be used in cancer ablation to deliver pulsed high-voltage but low-energy electric current to the cell membrane and to invoke cell death.

Characterization of the Pore Structure and Fluid Movability of Coal-Measure Sedimentary Rocks by Nuclear Magnetic Resonance (NMR).

Analyzing and mastering the pore structure and fluid movability characteristics of coal-measure sedimentary rocks is significant for the safe and effective development of unconventional resources. In this work, nuclear magnetic resonance (NMR) experiments were carried out on three common fine sedimentary rocks (i.e.