Publications by authors named "Shuaibo Yang"
Photodynamic therapy (PDT) and photothermal therapy (PTT) have emerged as promising treatment options, showcasing immense potential in addressing both oncologic and nononcologic diseases. Single-component organic phototherapeutic agents (SCOPAs) offer advantages compared to inorganic or multicomponent nanomedicine, including better biosafety, lower toxicity, simpler synthesis, and enhanced reproducibility. Nonetheless, how to further improve the therapeutic effectiveness of SCOPAs remains a challenging research area.
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- Researchers developed a biodegradable hollow mesoporous organosilica nanoparticle (HMON)-based nanoplatform for anticancer treatment, which combines chemotherapy and photothermal therapy.
- This new system can co-deliver paclitaxel and a photothermal agent (IR820) more effectively than previous methods, featuring a high drug-loading capacity of 28.4%.
- The nanoparticle design allows for controlled drug release in the tumor's environment and enhanced tumor suppression when combined with NIR laser irradiation, showing promising results for cancer therapy.