Publications by authors named "Shuai-Quan Li"
Detection of gene mutation and its clinical significance in children with acute lymphoblastic leukemia.
Zhongguo Dang Dai Er Ke Za Zhi
March 2022
Article Synopsis
- The study aimed to analyze the mutation rate of specific genes in children with acute lymphoblastic leukemia (ALL) and assess its clinical relevance.
- Out of 120 children studied, 29.2% had a certain gene mutation, with a notable prevalence in B-lineage ALL cases, and these mutations were often located at the 12th and 13th codons.
- Children with gene mutations displayed significantly lower 2-year overall survival rates compared to those without, particularly when combined with overexpression and high white blood cell counts at diagnosis.
[Expression of CC-chemokine Receptor 7 in Patiens with Multiple Myeloma and Its Relationship with Extramedullary Disease].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
April 2017
Objective: To investigate the expression of CC-chemokine receptor 7(CCR7) in patients with multiple myeloma(MM) and its correlation with clinical features of MM.
Methods: The level of CCR7 expression in bone marrow samples from 53 newly diagnosed MM patients was detected by flow cytometry(FCM). Statistical methods were used to analyze the correlation between CCR7 expression and clinical features, such as sex, age, M protein, peripheral blood cell count, biochemical indicators, plasma cell ratio of bone marrow, immunophenotype, osteopathy and extramedullary disease.
[Expression and Clinical Significance of CC-chemokine Receptor 7 in Adult Acute Leukemia].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
April 2016
Objective: To explore the expression of CC-chemokine Receptor 7 (CCR7) in adult acute leukemia patients, and to analyze the relationship of CCR7 expression with the clinical characteristics of patients.
Methods: The expression of CCR7 in bone marrow samples from adult acute leukemia patients were detected by flow cytometry (FCM), the relationship of CCR7 expression with the clinical characteristics of patients such as sex, age, WBC count, blast cell ratio, CD56 expression, molecular biology, cell genetics, risk stratification, extramedullary infiltration was analyzed.
Results: The expression rate of CCR7 in adult ALL and AML patients was 36.