Publications by authors named "ShuLin Wang"

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  • The article DOI: 10.1016/j.jot.2024.06.010 has been corrected for accuracy.
  • This correction ensures that readers are accessing the most reliable information.
  • It reflects ongoing efforts to maintain academic integrity and clarity in published research.
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Here we experimentally demonstrate the dynamics of Bloch-Zener oscillations (BZOs) in a synthetic temporal lattice formed by the optical pulses in coupled fiber loops. By periodically modulating the phases imposed to the optical pulses in linear driven lattices, a two-band Floquet system with tunable bandgaps is realized, and the related BZOs that occurred in this system are displayed. On this basis, by manipulating the phase difference and coupling angle of the synthetic lattice, the widths of 0-gap and -gap are tuned feasibly so that a wide variety of the interplays between Bloch oscillations and Landau-Zener tunneling (LZT) are exhibited.

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Background: Overweight is thought to affect the outcome of minimally invasive surgery. There is still a lack of controlled studies of laparoscopic pancreaticoduodenectomy (LPD) versus open pancreaticoduodenectomy (OPD) in overweight patients. This study was designed to compare short-term and long-term outcomes in overweight patients treated with LPD and OPD.

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  • This study investigates the effects of being overweight on surgical outcomes for patients undergoing laparoscopic pancreaticoduodenectomy (LPD), addressing current controversies regarding safety and feasibility.
  • A total of 432 patients were analyzed, but after an adjustment for bias, results showed that while overweight patients had a higher risk of certain complications like postoperative pancreatic fistula and delayed gastric emptying, overall mortality rates were similar between overweight and normal weight groups.
  • The findings suggest that LPD is both safe and feasible for overweight patients, with comparable long-term survival outcomes, but the authors call for more high-quality studies to further validate these results.
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Background: Single-cell RNA sequencing (scRNA-seq) technology has emerged as a crucial tool for studying cellular heterogeneity. However, dropouts are inherent to the sequencing process, known as dropout events, posing challenges in downstream analysis and interpretation. Imputing dropout data becomes a critical concern in scRNA-seq data analysis.

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Experimental demonstration of tunable temporal Goos-Hänchen shift (GHS) in synthetic discrete-time heterolattices with scalar and vector gauge potentials is reported. By using Heaviside-function modulation in two fiber loops, we create a sharp gauge-potential interface and observe temporal GHS for total internal reflection (TIR), which manifests as a time delay rather than a spatial shift. The TIR occurs as the incident mode falls into the band gap of transmitted region with band shifting by scalar and vector potential.

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  • Osteomyelitis (OM) is an inflammatory bone condition that leads to bone necrosis and disrupts normal bone remodelling processes, but the specific mechanisms behind this disruption are still unclear.
  • Researchers utilized single-cell RNA sequencing to analyze the differences in osteoclast lineages in human cortical bone across healthy, infected, and reconstructed states, applying various advanced techniques like t-SNE and gene expression assays.
  • Experimental models in mice were created to study the relationships between a newly identified lineage of osteoclasts and mesenchymal stem cells (MSCs), revealing effects on bone healing and differentiation potential during different remodelling phases.
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  • The lipase PaL from Pseudomonas aeruginosa catalyzes the specific breakdown of menthyl propionate to form L-menthol, but its action mechanism was unclear due to the lack of a 3D structure.
  • Researchers determined the crystal structure of PaL at a high resolution (1.80 Å) and found that its key catalytic residue, His302, is uniquely positioned on the surface, separate from other important residues.
  • Through advanced simulations, they observed how the enzyme changes shape when binding to a substrate, which helps explain its function and could inform future engineering efforts to enhance its selectivity for L-menthol.
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Aims: This study aimed to investigate the clinical characteristics and outcomes associated with culture-negative limb osteomyelitis patients.

Methods: A total of 1,047 limb osteomyelitis patients aged 18 years or older who underwent debridement and intraoperative culture at our clinic centre from 1 January 2011 to 31 December 2020 were included. Patient characteristics, infection eradication, and complications were analyzed between culture-negative and culture-positive cohorts.

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Refraction is a basic beam bending effect at two media's interface. While traditional studies focus on stationary boundaries, moving boundaries or potentials could enable new laws of refractions. Meanwhile, media's discretization plays a pivotal role in refraction owing to Galilean invariance breaking principle in discrete-wave mechanics, making refraction highly moving-speed dependent.

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  • Corruption of marine fish can cause over 25 billion euros in economic losses each year, and traditional preservatives have problems like being toxic and expensive.
  • Researchers created a new type of preservative from radish leftovers called R-CDs, which are safe, cheap, and good for the environment.
  • R-CDs not only prevent spoilage and protect fish from bacteria but also help keep salmon fillets fresh for an extra 4 days!
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  • The study evaluated the induced membrane technique (IMT) for treating infected segmental bone defects in 203 patients from 2012 to 2020 and identified factors leading to negative outcomes.
  • Infection recurred in 13.3% of patients, with an overall union rate of 85.2%, and the study found that multiple debridements and larger defect sizes increased the risk of complications.
  • The findings suggest IMT is effective, but certain modifiable factors can improve outcomes, allowing surgeons to better inform patients and tailor treatment plans.
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Background: The feasibility and safety of laparoscopic pancreatoduodenectomy (LPD) in elderly patients is still controversial. This study aimed to compare the clinical outcomes of LPD and open pancreatoduodenectomy (OPD) in elderly patients.

Methods: Clinical and follow-up data of elderly patients (≥ 65 years) who underwent LPD or OPD between 2015 and 2022 were retrospectively analyzed.

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Soil salinization is a global constraint that significantly hampers agricultural production, with cotton being an important cash crop that is not immune to its detrimental effects. The rhizosphere microbiome plays a critical role in plant health and growth, which assists plants in resisting adverse abiotic stresses including soil salinization. This study explores the impact of soil salinization on cotton, including its effects on growth, yield, soil physical and chemical properties, as well as soil bacterial community structures.

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  • * It focuses on the Sirtuins family, which may play a beneficial role in reducing the harmful effects of DOX through mechanisms like reducing inflammation, oxidative stress, and apoptosis.
  • * The study also identifies small-molecule compounds and natural substances that could regulate Sirtuins, offering promising avenues for preventing and treating DOX-induced cardiac injury.
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The use of enzymes to catalyze Henry reaction has advantages of mild reaction conditions and low contamination, but low enzyme activity of promiscuous catalysis limits its application. Here, rational design was first performed to identify the key amino acid residues in Henry reaction catalyzed by Lactococcal multidrug resistance Regulator (LmrR). Further, non-canonical amino acids were introduced into LmrR, successfully obtaining variants that enhanced the catalytic activity of LmrR.

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At least 10 million tons of seafood products are spoiled or damaged during transportation or storage every year worldwide. Monitoring the freshness of seafood in real time has become especially important. In this study, four machine learning algorithms were used for the first time to develop a multi-objective model that can simultaneously predict the shelf-life of five marine fish species at multiple storage temperatures using 14 features such as species, temperature, total viable count, K-value, total volatile basic‑nitrogen, sensory and E-nose-GC-Ms/Ms.

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Global seafood consumption is estimated at 156 million tons annually, with an economic loss of >25 billion euros annually due to marine fish spoilage. In contrast to traditional smart packaging which can only roughly estimate food freshness, an intelligent platform integrating machine learning and smart aerogel can accurately predict remaining shelf life in food products, reducing economic losses and food waste. In this study, we prepared aerogels based on anthocyanin complexes that exhibited excellent environmental responsiveness, high porosity, high color-rendering properties, high biocompatibility, high stability, and irreversibility.

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  • - The Sirtuins family, specifically SIRT6, plays a crucial role in protecting myocardial cells from damage and aging caused by the chemotherapy drug doxorubicin (DOX), as evidenced by its ability to inhibit oxidative stress and apoptosis in these cells.
  • - In laboratory tests, SIRT6 overexpression was shown to reduce aging markers and inflammatory factors linked to DOX exposure, while silencing SIRT6 worsened cardiomyocyte injury, indicating its protective effects against DOX-induced damage.
  • - Furthermore, SIRT6 enhances fatty acid oxidation-related gene expression through interaction with PPARα, and in animal models, its overexpression restored normal heart function, highlighting its potential as a therapeutic target for preventing DOX
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  • * PARP-1 is a well-known protein that might help treat cardiovascular diseases linked to DOX, but PARP-2, another member of the PARP family, has not been well studied in this context.
  • * This study reveals that reducing PARP-2 may protect heart cells from aging caused by DOX, while increasing PARP-2 worsens cell damage, indicating that targeting PARP-2 could be a promising approach for preventing DOX-related heart problems.
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Objective: This study aims to assess the feasibility and effectiveness of color doppler flow imaging (CDFI) technology and the Slow Flow HD imaging technique in identifying fetal pulmonary veins (PVs) in the first trimester (11-13 + 6 weeks), and further explore the factors affecting fetal pulmonary vein identification in early pregnancy.

Methods: Echocardiography and scanning of PVs were performed in 240 normal singleton fetuses in early pregnancy by using CDFI and slow flow HD techniques, to compare the ability of two methods to identify the PVs. Slow Flow HD technology was used to further investigate the difference of PVs identification at different gestational ages [group I (11-11 + 6 weeks), group II (12-12 + 6 weeks), group III (13-13 + 6 weeks)] and with different maternal body mass indices (BMI) (≥ 25 and < 25).

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Economic loss due to fish spoilage exceeds 25 billion euros every year. Accurate and real-time monitoring of the freshness of fish can effectively cut down economic loss and food wastage. In this study, a dual-functional hydrogel based on sodium alginate-co-pigment complex with volatile antibacterial and intelligent indication was prepared and characterized.

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Background: This study aimed to assess the association of baseline insulin resistance (IR) surrogates and their longitudinal trajectories with cardiovascular diseases (CVD) to provide a useful reference for preventing CVD.

Methods: This study was a prospective cohort study conducted in the 51st Regiment of the Third Division of Xinjiang Corps. A total of 6362 participants were recruited in 2016 to conduct the baseline survey, and the follow-up surveys in 2019, 2020, 2021, and 2022.

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Concurrent strength-ductility improvement of HfMoTaTiZr is achieved Cr addition and the underlying strengthening mechanism was discussed. 4.2 at% Cr addition into HfMoTaTiZr led to the formation of a Laves phase, in addition to the BCC phase.

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