A short review of the sustainable utilization of coal gangue in environmental applications.

The production of coal gangue, a by-product of coal mining and washing, is rapidly increasing due to growing energy consumption. As the accumulated coal gangue has not been appropriately utilized, this has resulted in a squander of resources, waste disposal problems, and environmental pollution issues. However, coal gangue, a form of solid waste, exhibits various potential applications in the field of recycling.

Revealing defect-bound excitons in WS monolayer at room temperature by exploiting the transverse electric polarized wave supported by a SiN/Ag heterostructure.

Two-dimensional (2D) transition metal dichalcogenide (TMDC) monolayers are promising materials for light-emitting devices due to their excellent electric and optical properties. However, defects are inevitably introduced in the fabrication of TMDC monolayers, significantly influencing their emission properties. Although photoluminescence (PL) is considered as an effective tool for investigating the defects in TMDC monolayers.

Dynamic control of the directional scattering of single Mie particle by laser induced metal insulator transitions.

Interference between the electric and magnetic dipole-induced in Mie nanostructures has been widely demonstrated to tailor the scattering field, which was commonly used in optical nano-antennas, filters, and routers. The dynamic control of scattering fields based on dielectric nanostructures is interesting for fundamental research and important for practical applications. Here, it is shown theoretically that the amplitude of the electric and magnetic dipoles induced in a vanadium dioxide nanosphere can be manipulated by using laser-induced metal-insulator transitions, and it is experimentally demonstrated that the directional scattering can be controlled by simply varying the irradiances of the excitation laser.

PTPN1/2 inhibition promotes muscle stem cell differentiation in Duchenne muscular dystrophy.

Duchenne muscular dystrophy (DMD) is a lethal disease caused by mutations in the gene that encodes dystrophin. Dystrophin deficiency also impacts muscle stem cells (MuSCs), resulting in impaired asymmetric stem cell division and myogenic commitment. Using MuSCs from DMD patients and the DMD mouse model , we found that PTPN1 phosphatase expression is up-regulated and STAT3 phosphorylation is concomitantly down-regulated in DMD MuSCs.

Dynamic modeling of variable speed left ventricular assist devices coupled to the cardiovascular system.

Background: Most of the modeling of the Left Ventricular Assist Devices (LVADs) coupled with the cardiovascular system is based on the assumption of constant rotational speed. Compared with the traditional inertial model, the validated hysteresis model can take into account the unsteady characteristics of LVADs, but it fails to work under the condition of variable speed modulation.

Method: This study takes into consideration the impact of speed variations on the unsteady hysteresis effects.

Ultrastable and Low-Threshold Two-Photon-Pumped Amplified Spontaneous Emission from CsPbBr/Ag Hybrid Microcavity.

Halide perovskite materials have garnered significant research attention due to their remarkable performance in both photoharvesting photovoltaics and photoemission applications. Recently, self-assembled CsPbBr superstructures (SSs) have been demonstrated to be promising lasing materials. In this study, we report the ultrastable two-photon-pumped amplified stimulated emission from a CsPbBr SS/Ag hybrid microcavity with a low threshold of 0.

Changes in early endosomes in rat hippocampal CA1 neurons after transient global cerebral ischaemia.

Introduction: Transient global ischaemia in rodents causes selective loss of hippocampal CA1neurons, but the potential involvement of endocytic pathways has not been fully explored. The aim of this study was to investigate the changes in early endosomes in the CA1 subfield after ischaemia and reperfusion.

Materials And Methods: A four-vessel occlusion (4-VO) model was established in Wistar rats to induce 13 minutes of global cerebral ischaemia.

Muscle stem cell dysfunction in rhabdomyosarcoma and muscular dystrophy.

Muscle stem cells (MuSCs) are crucial to the repair and homeostasis of mature skeletal muscle. MuSC dysfunction and dysregulation of the myogenic program can contribute to the development of pathology ranging from cancers like rhabdomyosarcoma (RMS) or muscle degenerative diseases such as Duchenne muscular dystrophy (DMD). Both diseases exhibit dysregulation at nearly all steps of myogenesis.

Hybrid Sequencing-Based Genomic Analysis of from Urinary Tract Infections Among Inpatients at a Tertiary Hospital in Beijing.

Background: Urinary tract infection (UTI) associated with poses a serious threat for inpatients. This study aimed to describe the genomic characteristics of causing UTI in a tertiary-care hospital in Beijing, China.

Methods: A total of 20 strains collected from 2020 to 2021 were performed whole-genome sequencing.

One-step preparation of a self-assembled bioconjugate nanovaccine against .

Brucellosis, caused by , is a severe zoonosis, and the current live attenuated vaccine cannot be used in humans due to major safety risks. Although polysaccharide antigens can be used to prepare the vaccine, their lower immunogenicity limits them from producing efficient and broad protection. In this study, we produced a high-performance bioconjugate nanovaccine against different species of by introducing a self-assembly nanoparticle platform and an O-linked glycosylation system into serotype O:9, which has an -polysaccharide composed of the same unit as .

Preparation of sulfur self-doped coal-based adsorbent and its adsorption performance for Cu.

The limited application of high-sulfur coal (HSC) and the increasing severity of copper pollution in solution are two pressing issues. To alleviate such issues, a sulfur self-doped coal-based adsorbent (HSC@ZnCl) was obtained by pyrolysis (850 °C, 60 min holding time) of HSC and ZnCl with a mass ratio of 1:0.5.

Genetic Engineering of ATCC 25955 for Bioconjugate Vaccine Applications.

Vaccination is considered the most effective means to fight against the multidrug-resistant strains of . In recent years, a potential protein glycan coupling technology has been extensively used in the production of bioconjugated vaccines. Here, a series of glycoengineering strains derived from ATCC 25955 were designed for protein glycan coupling technology.

A novel detection method for neuronal death indicates abnormalities in intracellular membranous components in neuronal cells that underwent delayed death.

Acute neuronal degeneration is always preceded under the light and electron microscopes by a stage called microvacuolation, which is characterized by a finely vacuolar alteration in the cytoplasm of the neurons destined to death. In this study, we reported a method for detecting neuronal death using two membrane-bound dyes, rhodamine R6 and DiOC(3), which may be associated with the so-called microvacuolation. This new method produced a spatiotemporally similar staining pattern to Fluoro-Jade B in kainic acid-damaged brains in mice.

Grid-adaptive Fourier pseudospectral time domain model for the light scattering simulation of atmospheric nonspherical particles.

PSTD (pseudospectral time domain) is recognized as one of the powerful models to accurately calculate the scattering properties of nonspherical particles. But it is only good at the computation in coarse spatial resolution, and large "staircase approximation error" will occur in the actual computation. To solve this problem, the variable dimension scheme is introduced to improve the PSTD computation, in which, the finer grid cells are set near the particle's surface.

Dimension-variable invariant imbedding (DVIIM) T-matrix computational method for the light scattering simulation of atmospheric nonspherical particles.

The invariant imbedding (IIM) T-matrix method has shown great potential in light scattering field. However, the T-matrix need to be calculated through the matrix recurrence formula derived from the Helmholtz equation, thus its computational efficiency is much lower than Extended Boundary Condition Method (EBCM). To alleviate this problem, the Dimension-Variable Invariant Imbedding (DVIIM) T-matrix method is presented in this paper.

Effects of different external factors on urban roadside plants for the reduction of airborne fine particulate matters.

With the progress of urbanization and industrialization in China, the consumption of fossil fuels blows up. The burning of fossil fuels releases large amounts of particulate matter, leads to smog, and the air quality is gradually getting worsen. Previous studies have shown that vegetation can effectively reduce airborne particles with different size fractions.

Enhancement of Immune Response of Bioconjugate Nanovaccine by Loading of CpG through Click Chemistry.

CpG is a widely used adjuvant that enhances the cellular immune response by entering antigen-presenting cells and binding with receptors. The traditional physical mixing of the antigen and CpG adjuvant results in a low adjuvant utilization rate. Considering the efficient delivery capacity of nanovaccines, we developed an attractive strategy to covalently load CpG onto the nanovaccine, which realized the co-delivery of both CpG and the antigen.

Numerical analysis of different cardiac functions and support modes on blood damage potential in an axial pump.

Background: Cardiac functions and support modes of left ventricular assist device (LVAD) will influence the pump inner flow field and blood damage potential.

Methods: Computational fluid dynamics (CFD) method and lumped-parameter-model (LPM) were applied to investigate the impacts of cardiac functions under full (9000 rpm) and partial (8000 rpm) support modes in an axial pump.

Results: The constitution of hemolysis index () in different components of the pump was investigated.

Dynamic characteristic modeling of left ventricular assist devices based on hysteresis effects.

Objective: The purpose of this study is to develop a new model for the dynamic characteristics of left ventricular assist devices (LVADs) interacting with the cardiovascular system under constant-speed modes.

Methods: A new hysteresis model is established on the basis of the hysteresis effect and turbomachinery principles. The simulation results from the hysteresis model were compared with the inertia model.

A bioconjugate vaccine against produced by engineered .

Brucellosis, mainly caused by is a widespread zoonotic disease worldwide, with no available effective vaccine for human use. Recently, bioconjugate vaccines against have been prepared in O:9 (YeO9), whose O-antigen structure is similar to that of . However, the pathogenicity of YeO9 still hinders the large-scale production of these bioconjugate vaccines.

GP73 is a promising indicator in HIV diagnosis and treatment: a one-year follow-up study.

Golgi protein 73 (GP73) has been recognized as a biomarker for evaluating liver diseases, although the serum profile of patients with HIV remains unclear. This study was designed to investigate the diagnostic values of serum GP73 in patients with HIV. A total of 92 patients with HIV and 60 healthy participants were selected, and serum samples were collected; 51 of 92 patients were followed up and all indicators were re-tested after 1 year.

Identification of potential antigenic peptides of Brucella through proteome and peptidome.

Background: Brucellosis, caused by Brucella spp., is a major zoonotic public health threat. Although several Brucella vaccines have been demonstrated for use in animals, Brucella spp.

Ultralow Threshold Lasing from a Continuous-Wave-Pumped SiN/CsPbBr/Ag Thin Film Mediated by the Whispering Gallery Modes of a SiO Microsphere.

Thin-film pervoskite lasers driven by a continuous wave (CW) laser with ultralow thresholds, which is crucial for the development of on-chip electrically driven lasers, have not yet been realized owing to the low excitation power density of the CW laser. Here, we reported the CW-laser-pumped lasing from a thin film of CsPbBr quantum dots (QDs) sandwiched by a SiN and a Ag thin film and mediated by the whispering gallery modes of a SiO microsphere. The stable photoluminescence from CsPbBr QDs with a quantum efficiency of ∼45% is realized by encapsulating with a thin SiN film.