Delicate changes of bioapatite mineral in pig femur with addition of dietary xylooligosaccharide: Evidences from Raman spectroscopy and ICP.

Bone mineral is strongly correlated with performance and health of animal bodies. The mineral bioapatite (BAp) is the dominant component in bone tissue. This study investigated mineralogical changes of BAp in pig femur by Raman spectroscopy and inductively coupled plasma optical emission spectrometry (ICP-OES).

Advances of Coagulation Factor XIII.

Objective: To provide a comprehensive literature review on roles of coagulation factor XIII (FXIII) in coagulation, wound healing, neoplasm, bone metabolism, and pregnancy.

Data Sources: All articles in PubMed with key words "Coagulation factor XIII", "wound", "leukemia", "tumor", "bone," and "pregnancy" with published date from 2001 to 2016 were included in the study. Frequently cited publications before 2000 were also included.

Outcome of anti-thymocyte immunoglobulin plus cyclosporine A for severe aplastic anaemia with chronic hepatitis B virus infection.

The influence of chronic hepatitis B virus (HBV) infection on the efficacy of intensive immunosuppressive treatment (IST) of severe aplastic anaemia (SAA) patients remains unclear. Previous reports on this topic have been mostly case reports or have had a relatively short follow-up. Eight SAA patients carrying chronic HBV infection and 24 matched patients without HBV at a ratio of 1:3 were included in this retrospective analysis.

Pseudorabies virus infection inhibits autophagy in permissive cells in vitro.

A large number of studies have demonstrated that autophagy is involved in the infection processes of different pathogens. Autophagy is now recognized as an essential component of innate and adaptive immunity. Several herpesviruses have developed various strategies to evade this antiviral mechanism.

Roles of afadin in the formation of the cellular architecture of the mouse hippocampus and dentate gyrus.

The hippocampal formation with tightly packed neurons, mainly at the dentate gyrus, CA3, CA2, and CA1 regions, constitutes a one-way neural circuit, which is associated with learning and memory. We previously showed that the cell adhesion molecules nectins and its binding protein afadin play roles in the formation of the mossy fiber synapses which are formed between the mossy fibers of the dentate gyrus granule cells and the dendrites of the CA3 pyramidal cells. We showed here that in the afadin-deficient hippocampal formation, the dentate gyrus granules cells and the CA3, CA2, and CA1 pyramidal cells were abnormally located; the mossy fiber trajectory was abnormally elongated; the CA3 pyramidal cells were abnormally differentiated; and the densities of the presynaptic boutons on the mossy fibers and the apical dendrites of the CA3 pyramidal cells were decreased.

Clinical Features of Patients with Castleman's Disease Complicated Systemic Lupus Erythematosus.

Objective To investigate the clinical features of patients with Castleman's disease (CD) and systemic lupus erythematosus (SLE). Methods According to the diagnostic information between 1994 to 2014 extracted from the database of the Medical Record Department of Peking Union Medical College Hospital (PUMCH),patients with CD and SLE were included. A thorough literature review utilizing the key words of "Castleman's disease","systemic lupus erythematosus","SLE",and "lupus" was performed in PubMed during the same period.

Antennal Transcriptome and Differential Expression Analysis of Five Chemosensory Gene Families from the Asian Honeybee Apis cerana cerana.

Chemosensory genes play a central role in sensing chemical signals and guiding insect behavior. The Chinese honeybee, Apis cerana cerana, is one of the most important insect species in China in terms of resource production, and providing high-quality products for human consumption, and also serves as an important pollinator. Communication and foraging behavior of worker bees is likely linked to a complex chemosensory system.

Developmental regulation of CYP3A4 and CYP3A7 in Chinese Han population.

CYP3A4 and CYP3A7 are generally served as the major adult and fetal liver forms, respectively, and exhibited a developmental switch during liver maturation. The objective of this study was to explore the potential mechanisms associated with the developmental switch of CYP3A4 and CYP3A7 in the Chinese Han population. We analyzed CYP3A4/7, nuclear receptors, and epigenetic modifications in human liver samples.

Hepatic expression of transcription factors affecting developmental regulation of UGT1A1 in the Han Chinese population.

Purpose: Complete or partial inactivity of UGT1A1, the unique enzyme responsible for bilirubin glucuronidation, is commonly associated with hyperbilirubinemia. We investigated the dynamic expression of UGT1A1, and that of the transcription factors (TFs) involved in its developmental regulation, during human hepatic growth in Han Chinese individuals.

Methods: Eighty-eight prenatal, pediatric, and adult liver samples were obtained from Han Chinese individuals.

Localization of nectin-2δ at perivascular astrocytic endfoot processes and degeneration of astrocytes and neurons in nectin-2 knockout mouse brain.

Nectins are Ca-independent immunoglobulin-like cell-cell adhesion molecules. In the nervous system, among four members (nectin-1, -2, -3, and -4), nectin-1 and -3 are asymmetrically localized at puncta adherentia junctions formed between the mossy fiber terminals and the dendrites of CA3 pyramidal neurons in the mouse hippocampus and heterophilic trans-interactions between nectin-1 and nectin-3 are involved in the selective interaction of axons and dendrites of cultured neurons. By contrast, nectin-2, which has two splicing variants, nectin-2α and -2δ, has not been well characterized in the brain.

Extracellular expression and antiviral activity of a bovine interferon-alpha through codon optimization in Pichia pastoris.

Interferons (IFNs) are the primary line of defense against infectious agents. In particular, IFN-α is an important antiviral cytokine and has a wide range of immune-modulating functions. Porcine and human IFN-α have been successfully prepared and play important roles in the prevention and therapy of viral diseases.

Frequent neuromonitoring loss during the completion of vertebral column resections in severe spinal deformity surgery.

Background Context: Intraoperative monitoring (IOM) is an essential method for preventing postoperative spinal deficits during posterior vertebral column resection (VCR) surgery for treatment of severe spine deformities, but the IOM features directing at VCR procedures are rarely reported and need to be further clarified.

Purpose: To evaluate an important surgical point that will lead to the IOM loss frequently, and then remind the surgeons to pay close attention to impending monitoring changes during posterior VCR surgery.

Study Design/setting: Retrospective study.

Quality evaluation of peony seed oil spray-dried in different combinations of wall materials during encapsulation and storage.

This study aimed at evaluating the performance of peony seed oil microencapsulated by spray drying during encapsulation and storage. Four different combinations of gum arabic (GA), corn syrup (CS), whey protein concentrate (WPC) and sodium caseinate (CAS) were used to encapsulate peony seed oil. The best encapsulation efficiency was obtained for CAS/CS followed by the CAS/GA/CS combination with the encapsulation ratio of 93.

Enhanced thermoelectric performance of CdO : Ag nanocomposites.

CdO : Ag nanocomposites with metallic Ag nanoparticles embedded in the polycrystalline CdO matrix were synthesized by the solid-state reaction method. The addition of Ag led to increased grain boundaries of CdO and created numerous CdO/Ag interfaces. By incorporating Ag into the CdO matrix, the power factor was increased which was probably due to the carrier energy filtering effect induced by the enhanced energy-dependent scattering of electrons.

Super color purity green quantum dot light-emitting diodes fabricated by using CdSe/CdS nanoplatelets.

Colloidal nanoplatelets (NPLs) have recently been introduced as semiconductor emissive materials for the fabrication of quantum dot light-emitting diodes (QLED) on account of their ultra-narrow photoluminescence (PL) linewidth. In this paper, we report a multilayer all solution-processed green QLED based on colloidal CdSe/CdS core/shell NPLs with a narrow PL full-width-at-half-maximum (FWHM) of 12 nm. Our characterization results reveal that this kind of NPL containing QLED exhibit a low operating voltage of 2.

Rare true-positive outcome of spinal cord monitoring in patients under age 4 years.

Background Context: Intraoperative monitoring (IOM) is becoming an essential component in spinal surgery, but there are many different viewpoints about it in patients under age 4 years.

Purpose: This study aims to report some IOM features in children under age 4 years.

Design/setting: This is a retrospective cases study.

Immune responses to modified live virus vaccines developed from classical or highly pathogenic PRRSV following challenge with a highly pathogenic PRRSV strain.

Modified live virus vaccines (MLVs) are used on swine farms to control porcine reproductive and respiratory syndrome virus (PRRSV). MLVs from classical PRRSV (C-PRRSV) provide some protection against emergent highly pathogenic PRRSV (HP-PRRSV). This study characterized the protective efficacy and immune response to MLVs from C-PRRSV (CH-1R) or HP-PRRSV (HuN4-F112) in a challenge using HP-PRRSV (HuN4).

Quantitative estimation of the replication kinetics of genotype 2 PRRSV strains with different levels of virulence in vitro.

Porcine reproductive and respiratory syndrome virus (PRRSV) has become an important pathogen for the swine industry, and has resulted in substantial economic losses. In 2006, highly pathogenic PRRSV (HP-PRRSV) belonging to genotype 2 was first identified in China. Here, the replication kinetics of genotype 2 PRRSV strains were estimated in vitro in MARC-145 cells and porcine alveolar macrophages (PAMs) using a TaqMan-based real-time quantitative reverse transcription polymerase chain reaction (RT-qPCR) assay.

Clinical spectrum and survival analysis of 145 cases of HIV-negative Castleman's disease: renal function is an important prognostic factor.

Castleman's disease (CD) is a rare lymphoproliferative disorder with clinical features and prognostic factors that are incompletely characterized. This retrospective single-center study reviewed the largest HIV-negative CD patient cohort (n = 145) to date. By clinical classification, we identified 69 patients (47.

Exploration of the Intraoperative Motor Evoked Potential.

Study Design: Prospective study.

Objective: The objectives of the study was to (1) seek a relation between motor evoked potential (MEP) and corresponding cervical cord function in cervical compression myelopathy (CCM) and (2) explore a high-sensitive MEP range that can predict the intraoperative monitoring change ahead in cervical spine surgery.

Summary Of Background Data: There have been lots of controversies concerning the application of transcranial MEP in cervical spine surgery.