[The clinicopathological analysis of 88 patients with abnormal liver function test of unknown etiology].

Objective: To evaluate the clinical and histological features of patients with abnormal liver tests of unknown etiology, and then to investigate the diagnosis and differential diagnosis.

Methods: Patients with abnormal liver function test hospitalized and had liver biopsies during 2008 - 2009 constituted this retrospective study cohort. After excluding those patients diagnosed with hepatotropic viral hepatitis, space occupying lesions of the liver, alcoholic liver disease and obstruction of bile duct caused by stone or malignancy and AMA/AMA-M(2) positive of primary biliary cirrhosis (PBC), the clinical and histological characteristics were evaluated.

[Comparison of two methods of isolation and culture of osteoclasts and the dynamic observation of bone resorption].

Objective: To study the origin, morphological structure, and functional regulation of osteoclast (OC) for further investigation on the mechanism and regulation of bone resorption.

Methods: The OCs were isolated by two kinds of traditional method. Osteoclasts were isoclated from neonatal rat long bones.

[Effect of genistein on the proliferation, differentiation and apoptosis of the osteoblasts].

Objective: To study the effect of genistein on the proliferation, differentiation and apoptosis of the osteoblasts in vitro.

Methods: The primary osteoblasts (OBs) were obtained from the rat calvaria and the cell line of osteosarcoma-UMR-106 served as control. The cells in the experiment group were grown in 10% (volume fraction) fetal calf serum (FCS) + alphaMEM + various concentrations of genistein.

[Central giant cell lesions of the jaws: a clinicopathological study of 31 cases].

Objective: To study the clinicopathologic features of central giant cell granuloma (CGCG) of the jaws and the relationship between the pathologic features and its clinical behavior.

Methods: Histologic, radiographic and follow-up information for 31 cases of central giant cell granuloma were reviewed. The histopathologic patterns were analyzed between nonrecurrent and recurrent cases for which the following-up information was available.

[Genistein inhibits the promotive effect of IL-1beta on osteoclastic bone resorption].

Objective: To investigate the effect of genistein, a soybean-derived isoflavone, on the stimulating effect on bone resorption of IL-1beta.

Methods: The osteoclasts (OCs) were isolated with the methods of Yu Shifeng. The rat calvaria were cultured as an organ.