Publications by authors named "Shu-zhen Gan"
Article Synopsis
- The study aimed to create a version of the suilysin protein that does not cause hemolysis (destruction of red blood cells) while still retaining its immune response capabilities.
- Researchers mutated the proline residue at position 353 to three different amino acids (alanine, leucine, and valine) and purified these recombinant proteins to test their hemolytic activity.
- Among the mutants, SLY(P353V) exhibited no hemolytic activity but still demonstrated significant immunogenicity in further tests.