A multifactorial screening model based on the Graves ophthalmopathy quality of life scores in dysthyroid optic neuropathy.

Purpose: To validate the Graves ophthalmopathy quality of life (GO-QOL) questionnaire in screening DON and to construct an effective model.

Methods: A total of 194 GO patients were recruited and divided into DON and non-DON (mild and moderate-to-severe) groups. Eye examinations were performed, and quality of life was assessed by the GO-QOL questionnaire.

Macular blood flow changes in dysthyroid optic neuropathy after high-dose intravenous pulse methylprednisolone (IVMP).

Objective: To investigate the changes in macular vessel density (VD) of the superficial layer of retina (SLR) and deep layer of retina (DLR) in dysthyroid optic neuropathy (DON) after high-dose intravenous pulse methylprednisolone (IVMP).

Materials And Methods: Eighteen DON patients (29 eyes) who completed high-dose IVMP and 16 healthy individuals (32 eyes) were enrolled in this study. Optical coherence tomography angiography (OCTA) image analysis and comprehensive ophthalmic examinations were performed, including the SLR macular whole-image VD (SLR-mwiVD) and DLR-mwiVD, best-corrected visual acuity (BCVA), the mean deviation of visual field (VF-MD), pattern standard deviation of visual field (VF-PSD) and the other parameters.

Ocular manifestations and quality of life in patients after hematopoietic stem cell transplantation.

Aim: To explore the relationship between ocular and systemic conditions and the impact of ocular complications on the quality of life (QOL) in patients after allogeneic hematopoietic stem cell transplantation (ALLO-HSCT).

Methods: Forty-four patients with severe hematopoietic disease were enrolled after ALLO-HSCT at our center from July 2018 to October 2020. They completed two questionnaires: the Ocular Surface Disease Index (OSDI) and the quality-of-life scale for Chinese patients with visual impairment (SQOL-DV1).

Decreased macular choriocapillaris in thyroid-associated ophthalmopathy: focusing on chorioretinal folds with and without optic disc edema.

Purpose: The aim of this study was to evaluate the vessel density (VD) of the macular choriocapillaris (CC) and retina in thyroid-associated ophthalmopathy (TAO) patients with chorioretinal folds (CRFs) with and without optic disc edema (ODE) and the correlations of these characteristics with visual function.

Method: This was a cross-sectional study. Twenty TAO patients with CRFs (35 eyes) and 20 normal subjects (normal group, 40 eyes) were recruited at the Ophthalmology Department of the Sun Yat-sen Memorial Hospital from March 2018 to October 2022.

Increased peripapillary capillaries in patients with acute leukemia by using optical coherence tomography angiography.

Purpose: To evaluate the radial peripapillary capillary vessel density (RPC-VD) and thickness of the retinal nerve fiber layer (RNFL) in acute leukemia (AL) and the associations of these characteristics with blood laboratory parameters.

Methods: A cross-sectional study was performed at the Ophthalmology Department of the Sun Yat-sen Memorial Hospital from February 2019 to April 2022. Sixty eyes of 30 patients diagnosed with AL and sixty eyes of 30 matched healthy controls were included.

Eye Habits Affect the Prevalence of Asthenopia in Patients with Myopia.

Purpose: This study aims to explore the risk factors of asthenopia in the myopic population.

Methods: In this cross-sectional study, myopia patients were inquired about their eye habits and were requested to complete an asthenopia questionnaire and ocular examinations. Age, gender, occupation, anisometropia, eye care education, weekly outdoor activity time, duration of continuous near work, daily screen time, dry eye, near phoria, and binocular accommodative facility were calculated using the Student's test-test, Mann Whitney test, and Pearson's chi-square test.

The Clinical Features of Graves' Orbitopathy with Elevated Intraocular Pressure.

Background: To investigate the clinical characteristics of Graves' orbitopathy (GO) with elevated intraocular pressure (IOP) using the European Group of Graves' Orbitopathy (EUGOGO) system.

Methods: In this retrospective study, the clinical data of GO patients with elevated IOP (≥21 mmHg) were collected in Sun Yat-sen Memorial Hospital from January 2010 to June 2016. The demographic characteristics, clinical history of thyroid disease and GO, and ocular examination data were evaluated, and the activity and severity of GO were classified.

Evaluation of the Graves' Orbitopathy-Specific Quality of Life Questionnaire in the Mainland Chinese Population.

Purpose: To study the clinical significance of the Graves' orbitopathy-specific quality of life (GO-QOL) questionnaire in mainland Chinese patients.

Methods: A cross-sectional study was performed at the Ophthalmology Department of the Sun Yat-sen Memorial Hospital from April 2017 to April 2018. Eighty-eight consecutive Graves' orbitopathy (GO) patients completed the two subscales of the GO-QOL questionnaire: visual functioning and appearance.

[Analysis of Component Spectral Characteristics of PM10-Bound PAHs and the Influence of Weather Conditions During Spring in Xiamen].

In order to study pollution status and distribution characteristics of PAHs in PM10 during the spring in city and suburban Xiamen. A total of 18 PAHs were analyzed in the aerosol samples collected in daytime and nighttime during 11th to 21st of April, 2013 in city and suburban Xiamen. Results showed diurnal variation of Σ PAHs in suburban was weaker than that in city.

Effect of 0.025% FK-506 eyedrops on botulinum toxin B-induced mouse dry eye.

Purposes: To investigate the effect of FK-506 eye drops on Botulinum toxin B (BTX-B)-induced mouse dry eye.

Methods: Forty-five CBA/J mice were followed up for 4 weeks after treatment with 0.025% FK-506, vehicle or 0.

[Size distributions and diurnal variations in the concentrations of polycyclic aromatic hydrocarbons in winter in urban and suburban Nanjing, China].

The contamination status and distribution characteristics of particulate polycyclic aromatic hydrocarbons (PAHs) were investigated in aerosols of urban and suburban Nanjing. A total of 17 PAHs were analyzed in the aerosol samples collected in daytime and nighttime during January 1st to 10th, 2010 in Nanjing University (NU) and Nanjing University of Information Science & Technology (NUIST). The PAH concentrations at the urban and suburban sites were 41.

[Size distribution characteristics of polycyclic aromatic hydrocarbons of PM10 in foggy days in the north suburb of Nanjing].

Based on meteorological data and aerosol samples from Nov.15 to Dec.30,2007 in the north suburb of Nanjing, size distribution characteristics of polycyclic aromatic hydrocarbons (PAHs) in PM10 in foggy and sunny days were studied, and the concentrations of 16 PAHs were analyzed by gas chromatography with mass selective detection (GC-MS).