Publications by authors named "Shu-wen Ye"
Temozolomide (TMZ) can cross the blood-brain barrier (BBB) and deliver methyl groups to the purine (guanine) bases of DNA, leading to mispairing during DNA replication and subsequent cell death. However, increased expression of the repair enzyme methyl guanine methyltransferase (MGMT), which removes methyl groups from purine bases, counteracts methylation by TMZ. We evaluated the anticancer potential of thymoquinone (TQ), a hydrophobic flavonoid that inhibits resistance and induces apoptosis in various cancer cells, both in vitro and in vivo.
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- A nomogram was created to predict stent dysfunction after TIPS placement in patients with hepatitis B cirrhosis, aiming to improve patient outcomes.
- A study involving 355 patients identified key risk factors like diabetes and previous splenectomy for building this predictive model.
- The nomogram demonstrated strong predictive ability and clinical usefulness, with good accuracy in both training and validation groups.
Objective: To explore the diameter of internal carotid artery by arterial phase imaging of multi-slice spiral computed tomography (CT).
Methods: A total of 260 routine brain CT scans of the examiner were performed. And the arterial phase images of carotid artery were acquired, observed and measured through a three-dimensional reconstruction workstation.