[The protection of elemene on injured HUVECs induced by hydrogen peroxide].

Objective: To evaluate the effect of elemene on the survival of normal human umbilical endothelial cells (HUVECs) and the protection of elemene on injured HUVECs induced by hydrogen peroxide (H2O2).

Methods: Normal HUVECs were treated with elemene 1-100 microg/ml for 24-72 hours, the survival rate of HUVECs was determined by tetrazolium assay (MTT). To evaluate the protective effect of elemene on HUVECs from H2O2 injury, HUVECs were injured by 1 mmol/L H2O2 and then different final concentrations of elemene were added before the injury.