Publications by authors named "Shu-shan Yan"

Article Synopsis
  • Mesenchymal stem cells (MSCs) can help control the immune system, which is important for fighting off diseases and infections.
  • They do this by releasing tiny particles called extracellular vesicles (EVs) that can send important signals to other cells in the body.
  • Research shows that these MSC-EVs could help with autoimmune diseases, where the immune system mistakenly attacks the body, making them useful for diagnosis and treatment.
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Gliomas are the most common type of malignant brain tumor. Studies have identified that miR‑15b is negatively correlated with cripto-1 expression in glioma cells, and these molecules serve an important role in cancer development and progression. The current study was undertaken to further examine the association between these two molecules.

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Objective: To evaluate the efficacy and safety of telaprevir combined with peginterferon alfa (Peg-IFNa) plus ribavirin (RBV) (collectively, TPR therapy) in patients with chronic hepatitis C (CHC) using a meta-analysis approach.

Methods: The Pubmed literature database was searched for randomized controlled trials of TRP therapy in CHC patients published between 2009 and 2011. The following outcome data was extracted for meta-analysis of efficacy: sustained virological response (SVR), defined as serum HCV RNA of less than 1000 copies/ml at end-of-treatment (week 24); rapid virological response (RVR), defined as serum HCV RNA of less than 1000 copies/ml at treatment week 4; recurrence, defined as serum HCV RNA of less than 1000 copies/mL at end-of-treatment and more than 1000 copies/ml at follow-up (week 24 after treatment completion).

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