Development research of latent fingermarks based on aggregation-induced emission technique.

Fingerprints hold evidential value for individual identification; a sensitive, efficient, and convenient method for visualizing latent fingermarks (LFMs) is of great importance in the field of crime scene investigation. In this study, we proposed an aggregation-induced emission atomization technique (AIE-AT) to obtain high-quality fingermark images. Six volunteers made over 1566 fingerprint samples on 17 different objects.

[Effect of Anti-Oxidative of Ethyl Pyruvate and Taurine on the Red Blood Cell Storage at 4 ℃].

Objective: To investigate the anti-oxidative effect of ethyl pyruvate (EP) and taurine (TAU) on the quality of red blood cells stored at 4±2 ℃, hemolysis, energy metabolism and lipid peroxidation of the red blood cells in the preservation solution were studied at different intervals.

Methods: At 4±2 ℃, the deleukocyte red blood cells were stored in the citrate-phosphate-dextrosesaline-adenine-1 (CPDA-1) preservation (control group), preservation solution with EP (EP-AS), and TAU (TAU-AS) for long-term preservation. The enzyme-linked immunoassay and automatic blood cell analyzer were used to detect hemolysis and erythrocyte parameters.

Screening and identification of differentially expressed long non-coding RNAs in multidrug-resistant tuberculosis.

Background: Efforts to eradicate tuberculosis are largely threatened by drug-resistant tuberculosis, particularly, multidrug-resistant tuberculosis (MDR-TB). Screening and identification potential biomarkers for MDR-TB is crucial to diagnose early and reduce the incidence of MDR-TB.

Methods: To screen the differentially expressed long non-coding RNAs in MDR-TB, the lncRNA and mRNA expression profiles in serum derived from healthy controls (HCs), individuals with MDR-TB and drug-sensitive tuberculosis (DS-TB) were analyzed by microarray assay and 10 lncRNAs were randomly selected for further validation by reverse transcription-quantitative real-time PCR(RT-qPCR).

Integrating serum microRNAs and electronic health records improved the diagnosis of tuberculosis.

Background: To verify the differential expression of miR-30c and miR-142-3p between tuberculosis patients and healthy controls and to investigate the performance of microRNA (miRNA) and subsequently models for the diagnosis of tuberculosis (TB).

Methods: We followed up 460 subjects suspected of TB, and finally enrolled 132 patients, including 60 TB patients, 24 non-TB disease controls (TB-DCs), and 48 healthy controls (HCs). The differential expression of miR-30c and miR-142-3p in serum samples of the TB patients, TB-DCs, and HCs were identified by reverse transcription-quantitative real-time PCR.

genetic polymorphisms are associated with tuberculosis susceptibility and clinical phenotype in a Western Chinese Han population.

Tuberculosis (TB) is one of the most common infectious diseases globally. The surfactant protein C (SFTPC), which is involved in innate immunity and surfactant function in the lung, may contribute toward the progression of TB. The aim of the present study was to preliminarily investigate the possible association of single nucleotide polymorphisms (SNPs) in the gene with TB susceptibility and clinical phenotypes in a Western Chinese Han population.

[Effects of feeding patterns after hospital discharge on increase rates of growth indices in preterm and low-birth-weight infants within 3 months after birth].

Objective: To study the effects of post-discharge formula (PDF) for preterm infants, breast milk (BM) and term infant formula (TF) on increase rates of body weight, length and head circumference in preterm and low-birth-weight infants (PLBWIs) from discharge to 3 months after birth, and to provide a reference for the choice of feeding pattern for PLBWIs.

Methods: A total of 407 PLBWIs discharged from the newborn departments of ten hospitals in Guangzhou City and Foshan City in Guangdong Province, China were chosen for this study. According to feeding pattern, they were assigned to three groups: PDF-fed (n=258), BM-fed (n=58) and TF-fed (n=91).

[Study on SNP polymorphism of mitochondrial DNA D-loop region from Nu ethnic population in Yunnan of China].

Objective: To investigate the mitochondrial single nucleotide polymorphism (SNP)of Chinese Nu ethnic population from Yunnan region of China and to provide basic database for ethnic origin investigation and forensic purpose.

Methods: Genomic DNA from the whole blood of 87 unrelated individuals was extracted by standard chelex-100. The sequence polymorphism was analyzed by PCR-based assay and using ABI 3730 Analyzer to detect many number of relatively common point mutations.

[Genetic polymorphisms of 5 X-STR loci in Yunnan Nu population].

Objective: To investigate the allele and genotype frequencies of DXS6804, DXS6799, DXS8378, DXS7130 and DXS7132 in unrelated individuals of Nu population and establish the related genetic database.

Methods: Five X-STR loci were analyzed by PCR followed PAGE and silver staining.

Results: The allele frequencies of the five X-STRs in Yunnan Nu population are in accordance with Hardy-Weinberg equilibrium.

[Polymorphism of nine STR locus in Nu population from Yunnan Province].

In this study,blood samples were randomly drawn from 84 unrelated Nu individuals. The polymorphism of nine STR loci and Amelogenin locus were determined by DNA GeneScan. The genetic database on the distribution of gene frequency on the nine STR loci was established, statistical results showed that the genotype distributions were in agreement with Hardy-Weinberg equation.

[STR polymorphisms in four Xinjiang ethnic groups in China].

Population genetic studies were performed in Xinjiang's Uygur, Sibe, Ozbek and Kirgiz. Allele frequency distributions were analyzed for ten loci, i.e.