Curcumin suppresses intestinal microvascular endothelial cells invasion and angiogenesis induced by activated platelets.

The present study investigated the effects and mechanism by which curcumin suppresses intestinal microvascular endothelial cells (INMECs) invasion and angiogenesis induced by activated platelets. INMECs were obtained from healthy rats, and divided into five groups: Control, platelets, platelets +2.5 µM curcumin, platelets +5.

MiRNA synergistic network construction and enrichment analysis for common target genes in small-cell lung cancer.

Background: Small-cell lung cancer (also known as SCLC) is an aggressive form and untreated patients generally die within about 3 months. To obtain further insight into mechanism underlying malignancy with this cancer, an miRNA synergistic regulatory network was constructed and analyzed in the present study.

Method: A miRNA microarray dataset was downloaded from the NCBI GEO database (GSE27435).

Ultravilolet-radiation-induced graft polymerization of acrylamide onto the melt-blown polypropylene filter element by dynamic method.

By dynamic method under UV irradiation, commercial melt-blown polypropylene (PPMB) filter element was modified with acrylamide (AAm) using benzophenone (BP) as initiator. Attenuated total reflection-Fourier transform infrared spectroscopy and scanning electron microscope verified that polyacrylamide chain was grafted on the fiber surface of PPMB filter element. Elemental content analysis with energy dispersive X-ray of fibers revealed that the polymerization content in the inner part of filter element was relatively higher than that in the outer.

Prolonged retrograde amnesia following sedation with propofol in a 12-year-old boy.

Propofol is commonly used for sedation in a variety of clinical settings, as well as for induction and maintenance of anesthesia. The ease with which propofol can be administered and titrated to clinical effect, in addition to its accepted safety profile, has made it the drug of choice for sedation in outpatient procedures, such as gastrointestinal endoscopy. While short-term amnesia is a well-known side-effect of propofol, we present the first documented case of prolonged retrograde amnesia following propofol administration in a pediatric patient.

Gas-initiation under UV and liquid-grafting polymerization on the surface of polysulfone hollow fiber ultrafiltration membrane by dynamic method.

Using the inner-surface of polysulfone hollow fiber ultrafiltration membranes as grafted layer, the method of gas-initiation and liquid-polymerization has been studied, which aimed to adjust the diameter of the pores in the membranes. The degree of polymerization varied with the changes of the parameters, such as irradiation time, monomer concentration, temperature and time of polymerization and soon. The results indicated that using benzophenone (BP) which is in a gaseous condition as photo-initiator, acrylamide as graft monomer, the polyacrylamide chain was grafted on the surface of membranes.

[Effects of PEG additives on structure and performance of blend membranes].

Polysulfone(PSf) /polymer A blend membranes are fabricated by phase inversion process from casting solution of PSf, polymer A, DMAc, and polyethylene glycol (PEG). The resulting membranes prepared by changing the molecular weight of PEG additives are characterized by scanning electron microscope observation, measurement of water flux and trypsin retention. Experiments of water flux show that water fluxes have non-liner relationship with PEG molecular weight.

Ultrastructural organization of GABA-like immunoreactive profiles in the weaver substantia nigra.

GABA-like immunoreactivity (GABA-LI) in the substantia nigra pars compacta (SNc) of mutant weaver mice was investigated at the electron microscope level. Eight-week-old homozygous mutant weaver mice, paired with wildtype littermates as controls, were perfused with a buffered paraformadehyde/acrolein solution. Sections containing the SN were immunocytochemically reacted with an antiserum to GABA using the peroxidase-antiperoxidase (PAP) procedure.