Publications by authors named "Shu-Zheng Yuan"
Article Synopsis
- The study investigates the mechanisms behind aortic dissection (AD) by analyzing public RNA sequencing datasets to identify key hub genes that could aid in diagnosis and treatment.
- Researchers used multiple analytical methods to screen for overlapping genes and created a protein-protein interaction network, ultimately identifying five top hub genes linked to AD.
- Further examination revealed specific hub genes upregulated in certain cell types associated with AD, suggesting they play roles in inflammation, glycolysis, tissue remodeling, and angiogenesis.
miR-199b-5p promoted chondrogenic differentiation of C3H10T1/2 cells by regulating JAG1.
J Tissue Eng Regen Med
November 2020
Mesenchymal stem cells (MSCs) are considered a promising candidate for use in cell-based therapy for cartilage repair. To promote understanding of the molecular control of chondrogenesis differentiation in MSCs, we compared the changes in microRNAs during in vitro chondrogenesis process of human bone-marrow mesenchymal stem cells (hBMSCs). MiR-199b-5p was up-regulated significantly during this process.
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