Publications by authors named "Shu-Zhan Li"
Association of concomitant H1 antihistamine and immune checkpoint inhibitor therapy on survival outcome and safety in patients with advanced primary lung cancer: a cohort study.
Wei-Hong Zhang Bing-Xue Li Chen-Xi Ma Jian Wang Fan Yang Shu-Zhan Li Jia-Li Zhang Li Zhou Run-Mei Li Liang Liu
Transl Lung Cancer Res
October 2024
Article Synopsis
- A study investigated the effects of short-term use of antihistamines alongside immune checkpoint inhibitors (ICIs) in patients with advanced lung cancer to see if it improved treatment efficacy and reduced immune-related side effects.
- The research analyzed 211 patient records, dividing them into two groups: 109 patients who received H1 antihistamines during ICI treatment and 102 who did not.
- Results showed significantly better median progression-free survival (12.7 months vs. 4.3 months) and overall survival (32.8 months vs. 18.1 months) in the experimental group, suggesting that H1 antihistamines may be beneficial as a complementary treatment.