[Effect of electroacupuncture on renal aging and renal phosphatidylinositide 3-kinase/protein kinase B signaling in aging mice].

Objectives: To observe the effect of electroacupuncture (EA) at "Baihui"(GV20) and"Shenshu"(BL23) on the morphological changes of aging kidney and phosphatidylinositol 3-kinase /protein kinases B (PI3K/Akt) signaling in SAMP8 mice, so as to explore its mechanisms of delaying renal aging.

Methods: A total of 20 seven-month-old male SAMP8 mice were randomly divided into model group and EA group, with 10 mice in each group. The normal group consisted of 10 male SAMR1 mice with the same age.

Atomically Precise Water-Soluble Graphene Quantum Dot for Cancer Sonodynamic Therapy.

Although water-soluble graphene quantum dots (GQDs) have shown various promising bio-applications due to their intriguing optical and chemical properties, the large heterogeneity in compositions, sizes, and shapes of these GQDs hampers the better understanding of their structure-properties correlation and further uses in terms of large-scale manufacturing practices and safety concerns. It is shown here that a water-soluble atomically-precise GQD (WAGQD-C ) is synthesized and exhibits a deep-red emission and excellent sonodynamic sensitization. By decorating sterically hindered water-soluble functional groups, WAGQD-C can be monodispersed in water without further aggregation.