Publications by authors named "Shu-Xin Yao"
BACKGROUND Patients with chronic ankle instability (CAI) can present with abnormal gait. The purpose of this study was to evaluate plantar pressure distributions and posture balance during walking in unilateral CAI patients. MATERIAL AND METHODS We recruited 24 unilateral CAI patients and 24 healthy individuals; plantar pressure analysis was conducted using the Footscan® 3D pressure system.
View Article and Find Full Text PDFThe behavior of γ-β/β phase transition in TiAl alloy doped with β stabilizers (V, Cr, Mn) are studied by using the first principles method. It is found that alloying addition as well as anharmonic lattice vibration and disordered atomic occupation contributes to enhance the stability of cubic structure and accordingly introduce the disordered β phase into the high-temperature microstructure. The formation of low-temperature β phase originates from not only the stabilization of cubic structure but also the destabilization of tetragonal structure.
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- * This study performed "Target-Pathway" network analysis to identify new potential drug targets for OS, using various databases and scientific literature, with a focus on tankyrase 2 (TNKS2).
- * The findings indicate that TNKS2 could serve as an effective target for OS treatment, as in vitro tests showed that inhibiting TNKS2 leads to cell cycle arrest and increased cell death.
Article Synopsis
- Osteoarthritis (OA) is a degenerative joint disease where inflammation worsens cartilage breakdown, and Hydroxytyrosol (HT) has shown potential in managing inflammation.
- * The study explores how HT affects autophagy (a cellular cleanup process) and inflammation in chondrocytes, specifically focusing on the role of Sirtuin 6 (SIRT6) as a mediator.
- * Results indicated that HT reduces inflammatory cytokines and boosts SIRT6 expression, suggesting it combats inflammation in chondrocytes through SIRT6-regulated autophagy, making HT a potential target for treating inflammatory diseases.*
Allicin, the main biologically active compound derived from garlic, exerts a broad spectrum of pharmacological activities and is considered to have therapeutic potential in many neurological disorders. Using an in vitro spinal cord injury model induced by glutamate treatment, we sought to investigate the neuroprotective effects of allicin in primary cultured spinal cord neurons. We found that allicin treatment significantly attenuated glutamate-induced lactate dehydrogenase (LDH) release, loss of cell viability and apoptotic neuronal death.
View Article and Find Full Text PDF[The influence of oxy-organics on the emission intensity of flame atomic emission spectrometry (FAES) of alkali metals].
Guang Pu Xue Yu Guang Pu Fen Xi
November 2006
Flame atomic emission spectrometry (FAES) is frequently used to analyze various alkaline elements. The effects of concentrated oxy-organics in water solution on the radiation intensity of alkaline elements FAES were studied. The species and concentration of oxy-organics may affect the radiation intensity variation amplitude of alkaline elements and also the tendency of the mutation can be different dramatically.
View Article and Find Full Text PDF[Studies on effects and mechanism of water immersion restraint stress on bile secretion in rats].
Zhongguo Ying Yong Sheng Li Xue Za Zhi
August 2006
Aim: To probe into the operation mechanism of stress, through the studies on the effects of bile secretion in rats at the condition of water immersion restraint.
Methods: The animals were divided into six groups (n=8): Group A: restraint alone under room temperature + saline; Group B: water immersion restraint + saline; Group C: restraint alone under room temperature + Atropine; Group D: water immersion restraint + Atropine; Group E: restraint alone under room temperature + Phentolamine; F group: water immersion restraint + Phentolamine.
Results: Compared with group A, the capacity of bile secretion in group B decreased significantly (P < 0.