LDH-A promotes malignant behavior via activation of epithelial-to-mesenchymal transition in lung adenocarcinoma.

Lactate dehydrogenase A (LDH-A) is a key enzyme during glycolysis, which increases the synthesis of related proteins and has elevated activity in cancer cells. The role of LDH-A in lung adenocarcinoma (LUAD) progression was investigated in the present study. Expression levels of LDH-A were assessed in LUAD samples, and the relationship between LDH-A expression status and the prognosis of LUAD patients was confirmed.

Metric characterizations for well-posedness of split hemivariational inequalities.

In this paper, we generalize the concept of well-posedness to a class of split hemivariational inequalities. By imposing very mild assumptions on involved operators, we establish some metric characterizations of the well-posedness for the split hemivariational inequality. The obtained results generalize some related theorems on well-posedness for hemivariational inequalities and variational inequalities in the literature.