Synopsis of recent research by authors named "Shu-Qian Tang"
- Shu-Qian Tang's research primarily focuses on understanding the role of bone marrow (BM) endothelial progenitor cells and their influence on hematopoiesis, particularly in conditions like aplastic anemia and poor graft function post-transplant.
- Recent findings highlight the involvement of dysfunctional BM endothelial progenitor cells and their regulatory mechanisms, such as the PPARδ pathway and glycolytic enzyme PFKFB3, in contributing to ineffective hematopoiesis and recovery post-chemotherapy.
- Additionally, Tang's work emphasizes the distinct functions of macrophage subtypes in megakaryopoiesis, revealing that M2 macrophages support this process through the PI3K-AKT signaling pathway, potentially offering insights for therapeutic strategies in hematological disorders.
