is a critical oncogenic driver and contributes to epithelial-mesenchymal transition in papillary thyroid carcinoma.

Background: Growing evidence has indicated that the (), frequently deregulated in almost all tumor types tested, acted as a pivotal contributor to both cancer initiation and progression. However, the role of in human papillary thyroid carcinoma (PTC) remains controversial. The aim of the study was to investigate the expression and potential function of in human PTC.

Predictive Value of Preoperative Multidetector-Row Computed Tomography for Axillary Lymph Nodes Metastasis in Patients With Breast Cancer.

Axillary lymph nodes (ALN) status is an essential component in tumor staging and treatment planning for patients with breast cancer. The aim of present study was to evaluate the predictive value of preoperative multidetector-row computed tomography (MDCT) for ALN metastasis in breast cancer patients. A total of 148 cases underwent preoperative MDCT examination and ALN surgery were eligible for the study.

Prognostic values of the inhibitor of DNA‑binding family members in breast cancer.

The inhibitor of DNA‑binding (ID) proteins are dominant‑negative modulators of transcription factors with basic helix‑loop‑helix (bHLH) structures, which control a variety of genes in cell cycle regulation. An increasing volume of evidence has demonstrated that the deregulated expression of IDs in several types of malignancy, including breast carcinoma, has been proven to serve crucial regulatory functions in tumorigenesis and the development of breast cancer (BC). The present study evaluated the prognostic values of the ID family members by investigating a set of publicly accessible databases, including Oncomine, bc‑GenExMiner, Kaplan‑Meier plotter and the Human Protein Atlas.

FoxM1 is a promising candidate target in the treatment of breast cancer.

Forkhead box protein M1(FoxM1) is a member of forkhead superfamily transcription factors. Emerging evidences have progressively contributed to our understanding on a central role of FoxM1 in human cancers. However, perspectives on the function of FoxM1 in breast cancer (BC) remain conflicting, and mostly were from basic research.

CCR10 activation stimulates the invasion and migration of breast cancer cells through the ERK1/2/MMP-7 signaling pathway.

CCR10, a member of the chemokine receptor subfamily, is overexpressed in several tumors and play a crucial role in cancer development and progression. However, the functions of CCR10 in breast cancer are unknown. Here, we detected the protein levels of CCR10 in breast cancer cells by western blotting, and examined CCR10 expression in breast cancer tissues via immunohistochemical assay.

[Database Establishing and Data Mining of Pulmonary Diseases Based on Clinical Works by Modern Famous Veteran Doctors of Chinese Medicine].

Objective: To explore syndrome and treatment laws for treating diseases of the pulmonary system by establishing database based on clinical works by modern famous veteran doctors of Chinese medicine (CM).

Methods: Clinical experience and literature of medical records in clinical works by modern famous veteran doctors of CM were taken as data source. Database was established by fields and program design.

[Transformation of inorganic nitrogen in slag-wetland during the start-up period].

Lab-scale subsurface flow slag-wetlands were constructed to study the removal efficiency and transformation processes of low-concentration inorganic N during the start-up period. As for ammonium-dominated wastewater, the removal rates of total nitrogen (TN), ammonium nitrogen (NH4(+)-N), nitrate nitrogen (NO3(-)-N) and nitrite nitrogen (NO2(-)-N) were 0.12 g x (m2 x d)(-1), 0.

hTERT extends proliferative lifespan and prevents oxidative stress-induced apoptosis in human lens epithelial cells.

Purpose: Telomerase is a specialized polymerase that catalyzes synthesis of telomeres in most eukaryotes. When introduced into somatic cells, it extends the proliferative lifespan and prevents replicative senescence. Whether it has similar functions in lens epithelial cells, especially in human lens epithelial cells (HLECs) remains to be determined.

Gravity travelling waves for two superposed fluid layers, one being of infinite depth: a new type of bifurcation.

In this paper, we study the travelling gravity waves in a system of two layers of perfect fluids, the bottom one being infinitely deep, the upper one having a finite thickness h. We assume that the flow is potential and the dimensionless parameters are the ratio between densities rho = rho(2)/rho(1) and lambda = gh/c(2). We study special values of the parameters such that lambda(1 - rho) is near 1(-), where a bifurcation of a new type occurs.