Synopsis of recent research by authors named "Shu-Mei Hwang"
- Shu-Mei Hwang's research primarily focuses on the enzymatic mechanisms of aminopeptidases, specifically examining the structure-function relationships in Escherichia coli enzymes.
- Her 2006 study highlighted the critical roles of specific residues, particularly tyrosine 387 and arginine 404, in the hydrolytic activity of aminopeptidase P, revealing that optimal catalysis occurs at neutral pH.
- The research employed techniques such as pH-rate profile analysis and site-directed mutagenesis to identify and confirm the importance of key catalytic residues in the enzyme's active site.
