The study aimed to determine how common the PLA2R1 antigen is in kidney biopsy samples from patients with idiopathic membranous nephropathy (IMN) and to understand its connection to the disease.
Out of 108 patients, 41 were diagnosed with IMN, and an immunofluorescence assay revealed that 85.37% of those with IMN tested positive for the PLA2R1 antigen, while it was absent in other types of kidney diseases.
Despite the high prevalence of PLA2R1 in IMN patients, the research found no significant differences in clinical measures like age or protein levels between those who were positive and negative for the antigen.