Effects of Polyvinyl Chloride Microplastics on the Reproductive System, Intestinal Structure, and Microflora in Male and Female Mice.

The pervasive use of plastics in numerous industrial sectors has resulted in the circulation of microplastics across diverse ecosystems and food chains, giving rise to mounting concerns regarding their potential adverse impacts on biological systems and the environment. The objective of this experiment was to investigate the distinct effects of microplastic-polyvinyl chloride (PVC) exposure on the reproductive system, intestinal tissue structure, and intestinal microbial flora of both male and female mice. A total of 24 4-week-old Kunming mice were randomly assigned to one of four groups: male control group (CM), female control group (CF), male PVC test group (PVCM), and female PVC test group (PVCF) (n = 6).

Protection of Mitochondria from Free Hydroxyls by Zn(7)- and Cd(7)- Metallothioneins.

Zn(7)- and Cd(7)-metallothioneins were prepared. Mitochondria were isolated from rat hearts. Mitochondria lipid fluidity, protein conformation and mobility were determined by using ESR spin label.