Symptomatic and Asymptomatic SARS-CoV-2 Infection and Follow-up of Neutralizing Antibody Levels.

Objective: To investigate neutralizing antibody levels in symptomatic and asymptomatic patients with coronavirus disease 2019 (COVID-19) at 6 and 10 months after disease onset.

Methods: Blood samples were collected at three different time points from 27 asymptomatic individuals and 69 symptomatic patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Virus-neutralizing antibody titers against SARS-CoV-2 in both groups were measured and statistically analyzed.

[The genetic features of drug resistance to group A streptococcus and macrolides antibiotics among pediatric patients in Beijing 2012].

Objective: To investigate the genetic features of drug resistance to group A streptococcus(GAS) and macrolides antibiotics among pediatric patients in Beijing 2012.

Methods: A total of 199 strains of GAS were collected from 36 hospitals in Beijing between May and July, 2012. All strains were isolated from oropharyngeal swabs.

[Analysis on the whole genome of the influenza H1N1 virus of the mild and severe cases in Beijing in 2009].

Objective: To explore the characteristics of the whole genome of the influenza H1N1 virus of the mild and severe cases in Beijing.

Methods: A total of 21 samples of throat swabs were collected from surveillance-designated hospitals between June and December in 2009, including 10 severe cases (4 death cases) and 11 mild cases. RNA of the virus were extracted,and the amplified primers of the whole genome were designed.

[Study on types of M protein gene in group A streptococcus isolated from children in Beijing, 2011].

Objective: To explore the distribution characteristics of the types of M protein gene (emm) in group A streptococcus (GAS) isolated from children in Beijing in the year 2011.

Methods: During May to July in 2011, a total of 3315 patients who were diagnosed scarlet fever or pharyngeal infection by doctors in pediatric outpatient and emergency units of 36 hospitals, were selected as subjects. Their throat swab samples were collected and isolated the strains of GAS.

[Characteristics and related factors related to the resistance on antibiotics among group A streptococcus strains isolated from children in Beijing, during May and July 2011].

Objective: To analyze the characteristics of antibiotic resistance on group A streptococcus isolated from pediatrics in Beijing in 2011, to provide reference for clinical drug administration.

Methods: Strains of group A streptococcus were collected from the Departments of Pediatrics in 36 hospitals at different Districts of Beijing, from May to July 2011. Minimal inhibitory concentrations (MIC) with ten antibiotics of these isolates were tested by VITEK 2 Compact method.

[The significance of different sample types in study of pandemic A (H1N1) influenza diagnosis].

Objective: To explore the value of different types of samples, including throat swabs, stools, bloods in pandemic A (H1N1) influenza diagnosis and virus shedding patterns.

Methods: From May to June in 2009, 135 samples were collected from 23 confirmed cases of pandemic influenza A (H1N1) infection, including 99 throat swabs, 14 stools, 11 bloods, 1 respiratory tract washing from 13 confirmed cases and 10 blood samples from other confirmed cases. The virus was detected by real-time RT-PCR, the antibody was detected by haemagglutination inhibition assay.

[Etiological characteristics of influenza A (H1N1) 2009 virus in Beijing].

Objective: To analyze the results of detection on influenza A (H1N1) 2009 virus in Beijing from May 2009 to December 2009 and to understand the epidemiologic characteristics during the pandemic period.

Methods: The study was conducted from the May 1 to December 27, 2009. A total of 101 852 throat swab samples were detected with the real-time RT-PCR assay by the Beijing Network Laboratory.

[A survey on serological epidemiology of influenza A (H1N1) 2009 in Beijing].

Objective: To investigate the immunological level against influenza A (H1N1) 2009 in Beijing and provide evidence to evaluate the developing trend of the disease.

Methods: Between Nov. 27, 2009 and Dec.

Serologic survey of pandemic influenza A (H1N1 2009) in Beijing, China.

Objective: To examine the frequency and distribution of antibodies against pandemic influenza A (H1N1 2009) [H1N1] in populations in Beijing and elucidate influencing factors.

Methods: In January 2010, a randomized serologic survey of pandemic influenza A (H1N1 2009) was carried out. Six districts that were randomly selected with a total of 4601 participants involved in the survey have their antibody level tested by hemagglutination inhibition assay.

Primary evidence for involvement of IP3 in heat-shock signal transduction in Arabidopsis.

The role of inositol 1,4,5-trisphosphate (IP(3)) in transducing heat-shock (HS) signals was examined in Arabidopsis. The whole-plant IP(3) level increased within 1 min of HS at 37 degrees C. After 3 min of HS, the IP(3) level reached a maximum 2.