and polymorphisms modified susceptibility to radiation-induced lens opacity in natural high background radiation area, China.

A population-based case-control study was conducted in Yangjiang and Enping areas in South China to assess whether the risk of lens opacity induced by natural high background radiation exposure is modulated by polymorphisms of and . A total of 133 cases who were diagnosed with cortical and posterior subcapsular (PSC) opacity were recruited, and 419 healthy controls were selected through counter-matching in terms of radiation status. Genomic DNA from all the participants was genotyped with the Illumina platform for four single nucleotide polymorphisms of (rs189037, rs373759, and rs4585) and (rs1042522).

Alteration of cytokine profiles in uranium miners exposed to long-term low dose ionizing radiation.

Objective: The aim of the study is to estimate the immune function through cytokine profiles in sera of uranium mines.

Methods: Antibody arrays were used to detect 50 cytokines in sera of uranium miners. Miners who had continuously worked underground for <5 years were treated as control group and those who worked for ⩾ 5 years as experimental group.