Quercetin phospholipid complex significantly protects against oxidative injury in ARPE-19 cells associated with activation of Nrf2 pathway.

Age-related macular degeneration (AMD) is a major cause of blindness worldwide. Oxidative stress plays a crucial role in the pathogenesis of dry AMD. Quercetin has potent anti-oxidative activities, but poor bioavailability limits its therapeutic application.

Preparation of naringenin/ β-cyclodextrin complex and its more potent alleviative effect on choroidal neovascularization in rats.

Choroidal neovascularization (CNV) is characterized by abnormal blood vessels growing from the choroid. Current remedies for CNV have not shown favorable therapeutic efficacy. It is urgent to identify and develop more safe and potent anti-CNV agents via multiple technologies.

[Prevention and treatment of age-related macular degeneration by extract of Fructus lycii and its constituents lutein/zeaxanthin: an in vive and in vitro experimental research].

Objective: To investigate the in vivo inhibition of extract of Fructus lycii (FL) on the expressions of cathepsin B (Cat B) and cystatin C (Cys C) in high-fat diet and hydroquinone (HQ) induced model mice with age-related macular degeneration (AMD), and to explore the in vitro effects of lutein and zeaxanthin on hydrogen peroxide (H2O2,) induced expressions of matrix metalloproteinase 2 (MMP-2) and tissue inhibitor of metalloproteinase 2 (TIMP-2) on ARPE-19 cells.

Methods: Fifty female 8-month-old C57BL/6 mice were recruited in this research. Ten mice fed with regular diet was taken as the age control group.

A generic eye model by reverse building based on Chinese population.

The human eye has ethnic difference, the existing typical eye models are based on western eyes. A generic eye model based on Chinese population is presented for the first time. The statistical analyzed ocular parameters based on measured data are used for the initial generic eye model, and the wavefront aberration data obtained at two different pupil diameters are used for reproduction by optimizing the initial generic eye model.

[Acupuncture for treatment of 40 cases of convergence insufficient asthenopia with exotropia].

Objective: To explore the therapeutic effect of acupuncture on convergence insufficient asthenopia with exotropia.

Methods: Eighty cases of convergence insufficient asthenopia with exotropia were randomly divided into an acupuncture group and an eye drug treatment group, 40 cases in each group. The acupuncture group were treated with acupuncture at Jingming (BL 1), Taiyang (EX-HN 5), Chengqi (ST 1), Hegu (LI4); the eye drug treatment group were treated with local dropping of Aiweiduo.