Publications by authors named "Shu-Fei Yuan"
Unlabelled: The clustered regularly interspaced short palindromic repeats and their associated proteins (CRISPR-Cas) system widely occurs in prokaryotic organisms to recognize and destruct genetic invaders. Systematic collation and characterization of endogenous CRISPR-Cas systems are conducive to our understanding and potential utilization of this natural genetic machinery. In this study, we screened 39 complete and 692 incomplete genomes of myxobacteria using a combined strategy to dispose of the abridged genome information and revealed at least 19 CRISPR-Cas subtypes, which were distributed with a taxonomic difference and often lost stochastically in intraspecies strains.
View Article and Find Full Text PDFMicroorganisms are important sources of lipolytic enzymes with characteristics for wide promising usages in the specific industrial biotechnology. The cellulolytic myxobacterium is rich of lipolytic enzymes in the genome, but little has been investigated. Here, we discerned 406 potential lipolytic enzymes in 13 sequenced genomes.
View Article and Find Full Text PDFInternal Promoters and Their Effects on the Transcription of Operon Genes for Epothilone Production in .
Front Bioeng Biotechnol
October 2021
Article Synopsis
- Scientists studied genes that help make special substances called epothilones, which help fight cancer.
- They found that these genes are organized in a large group and can have smaller parts inside them called internal promoters that help control their activity.
- By activating these internal promoters using a special tool, they discovered that it helps the genes work better, which could improve the amount of epothilones produced, especially in certain strains that normally make low amounts.