Publications by authors named "Shu Sing Kong"
Background: The clinical presentations of abusive head trauma can abruptly worsen, so the occurrence of seizures and changes of EEG can be variable according to patients' conditions. Since the changes of EEG background waves reflect the cortical function of children, we aimed to find out whether the timing of EEG background, epileptiform discharges and seizure patterns were associated with the outcomes of patients with AHT.
Material And Methods: Using seizure type and acute stage electroencephalographic (EEG) characteristics to assess adverse neurological outcomes in children with seizures secondary to abusive head trauma (AHT).
Article Synopsis
- The study investigates the clinical features of COVID-19 in pediatric patients in Taiwan, focusing on those aged 18 and under.
- The research included 38 pediatric patients from a Northern Taiwan hospital between May and June 2021, finding that asymptomatic cases accounted for nearly half of the sample.
- Key symptoms in symptomatic patients were fever, cough, nasal obstruction, and sore throat, with asymptomatic patients showing higher RT-PCR cycle threshold values, suggesting their infections may be less severe compared to symptomatic cases.
Background: The aim of this study was to examine the predictive value of amplitude-integrated electroencephalography (aEEG) on 12-month seizure outcomes of infants with neonatal hypoxic-ischemic encephalopathy (HIE) treated with therapeutic hypothermia.
Methods: We conducted this retrospective cohort study in a tertiary neonatal intensive care unit between May 2012 and September 2017. Neonates with HIE who received both therapeutic hypothermia (TH) and aEEG were enrolled.
Article Synopsis
- The study aimed to compare the prevalence and risk of thyroid diseases in patients diagnosed with myasthenia gravis (MG) to non-MG controls using Taiwan's health databases.
- The research included 5,813 MG patients and 29,065 matched controls, revealing that MG patients had a significantly higher prevalence of thyroid diseases at diagnosis (18.4% vs. 4.7% in controls) and faced a 2.36-fold increased risk of developing thyroid diseases post-diagnosis.
- The findings indicated that the cumulative probability of developing thyroid diseases over time was substantially greater for MG patients compared to the control group, highlighting a potential link between MG and thyroid conditions.
Despite the development of vaccines in 2006, rotavirus is still a major cause of acute gastroenteritis worldwide. This study was performed to analyze the presence of circulating rotaviruses before and after the introduction of rotavirus vaccines to allow phylogenetic comparisons of vaccine strains in northern Taiwan.Rotavirus genotyping and sequencing of rotavirus VP7 and VP4 PCR products were performed by Reverse Transcriptase Polymerase Chain Reaction and DNA autosequencing.
View Article and Find Full Text PDFThis study examined the characteristics of norovirus (NoV) gastroenteritis associated with convulsions in children and its molecular epidemiology. From July 2006 through December 2015, NoV infection was confirmed by the genome detection using reverse transcriptase polymerase chain reaction. Viral genotyping with strain validation was achieved using sequence analyses with Basic Local Alignment Search Tool genome identification.
View Article and Find Full Text PDFBackground: Myasthenia gravis is the most common disease affecting the neuromuscular junction. The most common etiology among patients with juvenile myasthenia gravis is the production of antibodies against the acetylcholine receptor. However, the clinical outcome in relation to serum levels of anti-acetylcholine receptor antibodies in juvenile myasthenia gravis has rarely been discussed.
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- This study focused on the impact of the Child Protection Act on child maltreatment in Taiwan, analyzing hospitalization rates for physical abuse from 1996 to 2013.
- Results showed a significant increase in hospitalization rates for abuse before 2005, followed by a decline after the Act was implemented in 2003.
- Despite the decrease in hospitalization rates, the proportion of in-hospital deaths among abused children remained unchanged, indicating a need for further improvements in child protection measures.
Background: Nitrous oxide (NO) is a commonly used inhaled anesthetic in outpatient dental procedures. However, the increasing recreational use of NO may result in vitamin B deficiency-related neurologic and psychiatric symptoms. The aim of this study was to demonstrate the clinical features of chronic NO abuse in pediatric patients.
View Article and Find Full Text PDFBackground: Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an anti-neuronal antibody-mediated inflammatory brain disease that causes severe psychiatric and neurological deficits in previously healthy patients. The aims of this study were to demonstrate the clinical characteristics of patients diagnosed with anti-NMDA receptor encephalitis and to compare the different treatment strategies among these patients.
Methods: Patients presenting with newly acquired psychiatric and/or neurological deficits were studied retrospectively from 2009 to 2017.