Supportive or Confining? The Impact of War Metaphors From the COVID-19 Pandemic on Persons With Disabilities in Mainland China.

Ensuring the well-being of persons with disabilities (PWDs) is a priority in the public sector during the coronavirus disease 2019 (COVID-19) pandemic. To contain this unprecedented public crisis in China, a set of nationwide anti-epidemic discourse systems centered on war metaphors has guided the epidemic's prevention and control. While the public is immersed in the joy brought by the stage victory, most ignore the situation of the disadvantaged PWDs.

Ang II-AT2R increases mesenchymal stem cell migration by signaling through the FAK and RhoA/Cdc42 pathways in vitro.

Background: Mesenchymal stem cells (MSCs) migrate via the bloodstream to sites of injury and are possibly attracted by inflammatory factors. As a proinflammatory mediator, angiotensin II (Ang II) reportedly enhances the migration of various cell types by signaling via the Ang II receptor in vitro. However, few studies have focused on the effects of Ang II on MSC migration and the underlying mechanisms.

Noninvasive Ventilation in Acute Hypoxemic Nonhypercapnic Respiratory Failure: A Systematic Review and Meta-Analysis.

Objective: To evaluate the effectiveness of noninvasive ventilation in patients with acute hypoxemic nonhypercapnic respiratory failure unrelated to exacerbation of chronic obstructive pulmonary disease and cardiogenic pulmonary edema.

Data Sources: PubMed, EMBASE, Cochrane library, Web of Science, and bibliographies of articles were retrieved inception until June 2016.

Study Selection: Randomized controlled trials comparing application of noninvasive ventilation with standard oxygen therapy in adults with acute hypoxemic nonhypercapnic respiratory failure were included.

A high mean arterial pressure target is associated with improved microcirculation in septic shock patients with previous hypertension: a prospective open label study.

Introduction: The effect of mean arterial pressure titration to a higher level on microcirculation in septic shock patients with previous hypertension remains unknown. Our goal is to assess the effect of mean arterial pressure titration to a higher level on microcirculation in hypertensive septic shock patients.

Methods: This is a single-center, open-label study.

MSCs modified with ACE2 restore endothelial function following LPS challenge by inhibiting the activation of RAS.

Angiotensin (Ang) II plays an important role in the process of endothelial dysfunction in acute lung injury (ALI) and is degraded by angiotensin-converting enzyme2 (ACE2). However, treatments that target ACE2 to injured endothelium and promote endothelial repair of ALI are lacking. Mesenchymal stem cells (MSCs) are capable of homing to the injured site and delivering a protective gene.

The effect of prone positioning on mortality in patients with acute respiratory distress syndrome: a meta-analysis of randomized controlled trials.

Introduction: Prone positioning (PP) has been reported to improve the survival of patients with severe acute respiratory distress syndrome (ARDS). However, it is uncertain whether the beneficial effects of PP are associated with positive end-expiratory pressure (PEEP) levels and long durations of PP. In this meta-analysis, we aimed to evaluate whether the effects of PP on mortality could be affected by PEEP level and PP duration and to identify which patients might benefit the most from PP.

Normolipemic papuloeruptive xanthomatosis in a child.

Normolipemic papuloeruptive xanthomatosis is a very rare skin disorder. We report a child with yellowish papular eruptions on the face that rapidly merged into confluent plaques. Serum lipid profiles showed normolipemia.

Binary sub-wavelength diffractive lenses with long focal depth and high transverse resolution.

This study explores two-dimensional binary sub-wavelength diffractive lenses (BSDLs) for implementing long focal depth and high transverse resolution based on the rigorous electromagnetic theory and the finite-difference time-domain method. Focusing performances, such as the actual focal depth, the ratio between the focal depth of the designed BSDL and the focal depth of the conventional sub-wavelength lens and the spot size of the central lobe at the actual focal plane, for different f-numbers, have been studied in the case of TE incidence polarization wave. The rigorous numerical results indicate that the designed BSDLs indeed have long focal depth and high transverse resolution by modulating the binary sub-wavelength characteristic sizes.

Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions.

The anticonvulsant carbamazepine (CBZ) frequently causes cutaneous adverse drug reactions (cADRs), including maculopapular eruption (MPE), hypersensitivity syndrome (HSS), Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). We reported that SJS/TEN caused by CBZ is strongly associated with the HLA-B*1502 gene in Han Chinese. Here, we extended our genetic study to different types of CBZ-cADRs (91 patients, including 60 patients with SJS/TEN, 13 patients with hypersensitivity syndrome and 18 with maculopapular exanthema versus 144 tolerant controls).

Multiple tumors of the follicular infundibulum.

Background: Tumor of the follicular infundibulum is an uncommon benign neoplasm manifested histopathologically by a superficial epithelial plate-like growth pattern with multiple thin epidermal connections comprised of monomorphic cells with abundant cytoplasm. Cases of multiple tumors of the follicular infundibulum are rare and are described as hypopigmented scar-like macules or flat papules on the face, neck, and upper chest.

Objective: The objective was to describe a case of multiple tumors of the follicular infundibulum with numerous pigmented macules or papules and extensive involvement including the face, neck, anterior and posterior trunk, upper extremities, and intertriginous areas.

Tunable high-peak-power, high-energy hybrid Q-switched double-clad fiber laser.

A cw laser-diode-pumped Yb-doped double-clad fiber laser operating in a hybrid Q-switched regime was demonstrated. The output pulses had a duration as short as 4.2 ns, a tunable wavelength range from 1080.

Narrow-linewidth widely tunable hybrid Q-switched double-clad fiber laser.

A laser-diode-pumped Yb-doped double-clad fiber laser operating in a hybrid Q-switched regime has been demonstrated. With pulsed pump light and stimulated Brillouin scattering of the gain fiber as the Q-switching mechanisms, the laser generated nanosecond pulses with a stable repetition rate. A single-pulse energy of as much as 143.