Publications by authors named "Shu Li Ma"

Article Synopsis
  • - Glyphosate-based herbicides (GBH) have been shown to cause liver toxicity in mice, leading to structural changes, inflammation, and mitochondrial damage after exposure to various doses over 30 days.
  • - The study revealed that GBH negatively impacted liver function and increased oxidative stress, affecting metabolic pathways related to gluconeogenesis and fatty acid synthesis.
  • - Researchers identified correlations between oxidative stress markers and specific gene expressions related to liver metabolism, offering new insights into how GBH leads to hepatotoxicity.
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Background: We aimed to explore the association between long-term exposure to particulate matter ≤ 2.5 µm (PM) and metabolic syndrome (MetS) and its components including fasting blood glucose (FBG), blood pressure, triglyceride (TG), high-density lipoprotein cholesterol (HDL-c) and waist circumference among adults and elderly in south China.

Methods: We surveyed 6628 participants in the chronic disease and risk factors surveillance conducted in 14 districts of Guangdong province in 2015.

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Article Synopsis
  • * While TBI mortality remained stable, SCI mortality surged by 148.3%, with higher rates observed in males, rural residents, and the elderly.
  • * The leading causes of TBI deaths were motor vehicle crashes for younger individuals and falls for older adults, highlighting the need for enhanced injury prevention and treatment strategies.
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We hypothesized that exposure to polluting fuels for cooking was associated with abnormality of glucose metabolism and diabetes mellitus (DM) in south urban China. 3414 residents were surveyed in 14 urban areas of Guangdong Province in 2018. We recorded polluting fuels for cooking exposure, different DM status (DM, prediabetes), fasting blood glucose (FBG), oral glucose tolerance test (OGTT), glycated hemoglobin (HbA ), and other covariates by using a structured questionnaire.

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  • - We analyzed injury mortality trends in southern China during COVID-19, comparing data from January to June 2020 with the same months in 2019 in Guangdong province.
  • - Overall, all-cause injury deaths significantly dropped from 28.65 to 23.24 per 100,000, but notable increases in self-harm deaths (over 139%) were observed in the 10-14 age group and some rises in older age groups.
  • - The findings suggest lower mortality for most injury types during the pandemic, but highlight the need for targeted prevention measures, particularly for self-harm and other injuries in vulnerable populations.
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Objectives: To analyse the patterns of transition of health burden for 110 causes of death by stratification of age, sex and geographic regions in Guangdong between 2005 and 2015.

Methods: We analysed the age-specific, sex-specific, region-specific mortality in Guangdong based on assembled databases. County-level surveillance data were calculated to inform city-level changes.

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Objectives: We sought to investigate the association between household exposure to biomass fuel and metabolic syndrome (MetS) and its components including blood pressure, triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), fasting blood glucose (FBG) and waist circumference among females in southern rural China.

Methods: We surveyed 1664 residents in the Chronic Disease and Risk Factors Surveillance, conducted in 14 districts of Guangdong province. We recorded the use of biomass fuel, MetS and its components, and other covariates by using a structured questionnaire.

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Accumulating evidence has suggested the involvement of long noncoding RNAs (lncRNAs) on the acute myeloid leukemia (AML). Therefore, this study aimed to investigate the unknown function of lncRNA Prostate cancer-associated transcript-1 (PCAT-1) in AML cells. Our data found that PCAT-1 was highly expressed in AML-M1/2 and AML-M3 patients than normal controls and its expression was significantly up-regulated in AML cell lines Kasumi-6 and HL-60.

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