Publications by authors named "Shu Fan Zhou"
Article Synopsis
- The study explored how Wangbi Tablets can help treat knee osteoarthritis (KOA) by analyzing clinical symptoms, related genes, and drug-target interaction networks at different stages of the disease: acute, remission, and recovery.
- Researchers used databases to identify clinical data and potential targets of the tablets, applying methods like Jaccard and cosine similarity to compare them with KOA symptoms and pathways.
- The findings indicated that Wangbi Tablets are particularly effective during the remission and recovery phases, targeting inflammation and pain, and demonstrating antioxidant properties, which collectively help alleviate symptoms like knee pain and joint swelling.
In this study, we aimed at studying the effects of engineered and patterned substrates on the migration characteristics of mammalian cancer cell lines. On the shallow topographical patterns, cells from different histological origins showed different migration speed and directionality. We also observed that cells from the same origin showed distinctive behaviour, suggesting these substrate topographies could distinguish cancer subtypes.
View Article and Find Full Text PDFOn a microgrooved substrate, cells migrate along the pattern, and at random positions, reverse their directions. Here, we demonstrate that these reversals can be controlled by introducing discontinuities to the pattern. On "V-shaped grating patterns", mouse osteogenic progenitor MC3T3-E1 cells reversed predominately at the bends and the ends.
View Article and Find Full Text PDFWe report on an apodization scheme for terahertz fiber Bragg gratings. The grating consists of only 90 ablated notches on two opposite sides of a subwavelength polymer fiber. The grating strength can be effectively tuned by controlling the longitudinal shift between the two-sided notches, and apodization can be achieved by applying an envelope profile.
View Article and Find Full Text PDFTransmission filters for the terahertz domain having a shaped bandpass have been modeled and demonstrated. The filter designs were based on the desired filter type and bandwidth, and implemented by cascading quarter wave phase shifted fiber Bragg gratings written in Topas polymer subwavelength fiber. As an example, a 5-pole Chebyshev filter with <3 GHz bandwidth was designed and fabricated.
View Article and Find Full Text PDFArticle Synopsis
- Researchers have successfully created fiber Bragg gratings in polymer fibers specifically for the terahertz (THz) window, marking a first in the field.
- The notch-type gratings were inscribed using a KrF excimer laser at a wavelength of 248 nm in a subwavelength Topas fiber, achieving a significant transmission loss of 60 dB for short gratings with 192 notches.
- These gratings have promising potential applications in THz signal filtering and in chemical or biosensing technology.