Publications by authors named "Shruti Tadachina"
Iran J Pathol
December 2023
Article Synopsis
- Colorectal carcinoma (CRC) is a prevalent cancer that can evade immune responses through the PD-1/PD-L1 interaction, making immunotherapy with checkpoint inhibitors essential for treatment.
- A 2-year study analyzed PD-L1 expression in 34 CRC specimens to understand its relationship with various clinicopathological factors.
- The findings showed PD-L1 positivity in 17.65% of both tumoral cells and immune cells, linking PD-L1 expression with poor prognostic indicators, suggesting its potential utility in targeted therapy for CRC.
