Dual mechanism (sunlight/dark) of the self-assembly nitazoxanide drug on cellulose nanocrystal surface for destroying the Cryptosporidium parvum oocysts.

Destruction of the cryptosporidium parvum (C. parvum) Oocysts is the main target of the work via the improvement effect of the nitazoxanide (NTZ) drug by increasing the drug adsorption process without changing the cell viability. The synthesis of a self-assembly nanocomposite (NCP) of cellulose nanocrystals (CNC) and NTZ drug was performed successfully via the chemical precipitation methods without utilizing the temperature.