Publications by authors named "Shrook Mousa"
Methods And Results: The study included 200 Egyptian subjects. They were divided into four equal groups: group 1: obese patients with NAFLD and T2DM (O+/NAFLD+/DM+), group 2: nonobese patients with NAFLD and T2DM (O-/NAFLD+/DM+), group 3: obese nondiabetic patients with NAFLD (O+/NAFLD+/DM-), and group 4: nonobese healthy control subjects. Plasma adiponectin was measured using ELISA (enzyme-linked immunosorbent assay) technique.
View Article and Find Full Text PDFPurpose: The purpose of this study was to assess the possible clinical effects of vitamin K4 supplementation in individuals with type 2 diabetes namely insulin resistance, glycaemic control, and lipid profile.
Methods: This was a prospective randomised double-blind placebo-controlled clinical trial. A total of 106 patients were randomised to receive either 1 mg of vitamin K4 (menadiol diacetate) or placebo for 24 weeks.
Polycystic ovary syndrome (PCOS) is the commonest endocrine disorder in females in the reproductive period with estimated prevalence of 5% to 18% [1]. It contributes to the mortality and morbidity in patients with PCOS due to the increased risk of different metabolic and cardiovascular (CV) complications [2]. Despite the presence of obesity in 40-60% of cases [3], the disease may occur in non-obese women.
View Article and Find Full Text PDFBackground And Aims: SARS-CoV-2 infection has been recorded in 230 countries to date. Obesity has a negative impact on one's quality of life and is one of the main causes of mortality globally. Obesity affects the immune system, making the host more susceptible to infectious infections.
View Article and Find Full Text PDFThe risk of micro and macrovascular disease in Egyptian patients with diabetes and peripheral arterial disease.
J Community Hosp Intern Med Perspect
March 2021
Article Synopsis
- The study focused on the prevalence of micro- and macrovascular diseases in Egyptian patients with diabetes mellitus (DM) and peripheral arterial disease (PAD), involving 161 patients, mostly with type 2 DM.
- A notable percentage of participants had abnormal ankle/brachial index (ABI) results, indicating varying levels of PAD, with significant correlations found between abnormal ABI and factors like diabetes duration, ischemic heart disease, and neuropathy.
- The findings suggest a high risk of vascular diseases among these patients, emphasizing the importance of early diagnosis and effective management of risk factors to slow down PAD progression.
In type 2 diabetes mellitus (T2DM), hyperglycemia leads to oxidative insult. Vitamins A and E have antioxidant potentials and may help in managing diabetes. The combined effect of high-dose vitamin A plus E supplementation with and without zinc on T2DM, has never been examined.
View Article and Find Full Text PDFObjective: We assessed plasma adiponectin and its correlation with carotid intima-media-thickness (CIMT), as a marker of atherosclerosis, and urine albumin/creatinine ratio (ACR) in patients with non-alcoholic fatty liver disease (NAFLD).
Methods: The study included 100 Egyptian subjects (50 patients with NAFLD with no history of diabetes or hypertension and 50 age and sex-matched normal healthy control subjects). Urine albumin/creatinine ratio (ACR) was assessed in all participants and fasting plasma adiponectin was measured using ELISA technique.
Article Synopsis
- Hypothyroidism is linked to a higher risk of atherosclerosis, with artery stiffness measured by pulse wave velocity (PWV) providing a noninvasive assessment of this condition.
- The study assessed 100 Egyptian females with varying levels of hypothyroidism and found that those with overt and subclinical hypothyroidism had significantly higher PWV compared to a control group.
- A positive correlation was noted between thyroid-stimulating hormone (TSH) levels and PWV, suggesting that as hypothyroidism severity increases, so does the risk of early atherosclerosis.
Article Synopsis
- The study examined thyroid functions and levels in 150 pregnant Egyptian women across all three trimesters, comparing them to a control group of non-pregnant women.
- Serum thyroid stimulating hormone (TSH) levels were significantly lower in pregnant women than in non-pregnant women, with trimester-specific TSH reference ranges established.
- Thyroid peroxidase antibodies (TPO Abs) were highest in the first trimester and decreased in subsequent trimesters, while thyroid volume was slightly higher but not significantly compared to controls, and positively correlated with body mass index.
Hypothyroidism is associated with increased risk of atherosclerosis. We assessed carotid intima-media thickness (CIMT), as a marker of atherosclerosis, and endothelial function in patients with hypothyroidism. We included 70 female patients with hypothyroidism in the study, 40 patients with overt and 30 patients with subclinical hypothyroidism.
View Article and Find Full Text PDFPlasma adiponectin and carotid intima-media thickness in non-obese patients with type 2 diabetes.
J Diabetes Complications
August 2015
Aim: We assessed the correlation between plasma adiponectin levels and carotid intima media thickness (IMT), as a marker of atherosclerosis, in non-obese patients with type 2 diabetes.
Methods: The study group included 112 (60 males and 52 females) non-obese Egyptian patients with type 2 diabetes. Fasting plasma adiponectin was measured using ELISA technique.