Publications by authors named "Shriya Sawant"

Background: Because little is known about the impact of implant surface modifications on the peri-implant microbiome, we aimed to examine peri-implant communities in various surface types in order to better understand the impact of these surfaces on the development of peri-implantitis (PI).

Methods: One hundred and six systemically healthy individuals with anodized (AN), hydroxyapatite-coated (HA), or sandblasted acid-etched (SLA) implants that were >6 months in function were recruited and categorized into health (H) or PI. Peri-implant biofilm was analyzed using 16S rRNA gene sequencing and compared between health/disease and HA/SLA/AN using community-level and taxa-level metrics.

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Article Synopsis
  • Dysbiosis in the oral microbiome is linked to the development of oral cancer and is influenced by tobacco chewing, which is common in South Asia.
  • The study utilized 16S rRNA amplicon sequencing to examine the oral bacteria in Indian patients with oral cancer and tobacco users, discovering distinct microbial profiles between these groups and healthy controls.
  • Specific bacteria, such as Leptotrichia and Treponema, were found to be more prevalent in tobacco chewers, while Pseudomonas and Capnocytophaga were associated with oral cancer, suggesting potential biomarkers for early diagnosis in high-risk populations.
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Essential oils (EOs) are naturally occurring volatile aromatic compounds extracted from different parts of plants. They are made up of components like terpenes, phenols, etc., and are chemically unstable and susceptible to oxidative deterioration, leading to reduced shelf-life and overall degradation of the product.

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Squamous cell carcinoma is a highly aggressive type of oral cancer (OC). It is the most common cancer among men, and accounts for almost 90 % of all oral cancers in India. Consumption of tobacco is a leading factor contributing to maximum oral cancer incidences as per the WHO.

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