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Publications by authors named "Shristi Roy"

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Design, Synthesis, Molecular Docking, Pharmacokinetic Properties, and Molecular Dynamics Simulation of Sulfonyl Derivatives of Benzimidazole against Parkinson's Disease.
Subarna Roy Subhankar Basak Shristi Roy Paromita Dey Hema Barman

Curr Med Chem

October 2024

Article Synopsis
  • Parkinson's disease (PD) is a rapidly increasing global health issue with no cure, prompting the need for new drug development.
  • The study focused on synthesizing and testing sulfonyl derivatives of benzimidazole as potential treatments by targeting monoamine oxidase B (MAO-B) using molecular docking techniques.
  • Results showed that two synthesized compounds exhibited strong binding affinities, suggesting they could be promising candidates for effective PD therapies compared to existing drugs.
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